Macroporous graphene capped Fe3O4 for amplified electrochemiluminescence immunosensing of carcinoembryonic antigen detection based on CeO2@TiO2

Yang, Lei; Zhu, Wenjuan; Ren, Xiang; Khan, Malik Saddam; Zhang, Yihe; Du, Bin; Wei, Qin

doi:10.1016/j.bios.2017.01.055

Cited by 105 publications

(25 citation statements)

References 30 publications

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“…TiO 2 nanotubes (TiO 2 NTs) have a special tubular structure which could reduce the obstruction of electron transfer, facilitate electron transfer, suppress electron‐hole recombination, and effectively enhance its photoelectric properties. Therefore, it has been widely used in electrochemical detection , photocatalytic detection , electrochemical luminescence detection , and photoelectrochemical detection systems . However, the wider band gap of TiO 2 (3.2 eV) leads to lower efficiency in solar energy utilization since only ultraviolet light (<387 nm) can be absorbed by TiO 2 .…”

Section: Introductionmentioning

confidence: 93%

A Sensitive Photoelectrochemical Aptasensor for miRNA‐21 Based on the Sensitization Effect of CdSe Quantum Dots

et al. 2018

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A novel photoelectrochemical aptasensor for the sensitive detection of miRNA‐21 was designed based on the sensitization effect of CdSe quantum dots as a signal amplification strategy. The TiO2NTs/RGO/AuNPs electrode was prepared by the electrodeposition of graphene oxide and Au nanoparticles on TiO2 nanotubes with electrochemical reduction. The electrode was prepared as the matrix of the electrochemical aptasensor. The hairpin DNA strands decorated with CdSe quantum dots were immobilized on the surface of the electrode by Au−S bonds. Because of the card‐type structure of the hairpin DNA (HP‐DNA), the CdSe quantum dots were close to the base electrode, which would lead to the sensitization effect and cause the increase of the photocurrent intensity. When a certain concentration of the miRNA‐21 was added, miRNA‐21 hybridized with the complementary part of the HP‐DNA. At the same time, the hairpin structure of HP‐DNA was broken into a straight chain structure, so the CdSe quantum dots on the end of the DNA would move away from the electrode surface, the sensitization effect would be weakened, and the photocurrent intensity would be decreased. The designed photoelectrochemical aptasensor exhibited a low detection limit of 5.6 fM and a wide linear range from 20 fM to 0.2 nM, and it also showed good specificity, reproducibility and stability. The signal amplification strategy was also expected to provide a significant photoelectrochemical biosensor platform for the sensitive detection of biomolecules.

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Section: Introductionmentioning

confidence: 93%

A Sensitive Photoelectrochemical Aptasensor for miRNA‐21 Based on the Sensitization Effect of CdSe Quantum Dots

et al. 2018

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“…In the case of noble metals are relatively more expensive, which hamper the commercial application of the non -enzymatic glucose sensor. Thus, metal oxide based nanostructure is not only used in glucose sensor applications, but also applicable in the field of electrochemical immunosensor because of their lower cost, controllable synthesis, functional biocompatibility, chem- 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 ical stability, enhanced electron-transfer kinetics, and strong glucose adsorption capabilities [26,28,[32][33][34][35][36][37]. Metal oxides such as CuO and Co 3 O 4 have established a great deal of attention owing to the environmentally friendly nature and relatively good conductivity, simple synthesis process, superior electrochemical property, and good chemical stability.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Hierarchically Structured MOF‐Co₃O₄ on Well‐aligned CuO Nanowire with an Enhanced Electrocatalytic Property

Muthurasu

Kim

2019

Electroanalysis

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Engineering appropriate shape and size of three‐dimensional inorganic nanostructures materials is of one the main critical problems in pursuing high‐performance electrode materials. Herein, we fabricate a metal‐organic framework derived cobalt oxide (Co3O4) are grown on copper oxide nanowire (CuO NWs) supported on the surface of 3D copper foam substrate. The highly aligned CuO NWs were prepared by using electrochemical anodization of copper foam in ambient temperature and followed by MOF Co3O4 was grown via a simple in situ solution deposition then consequent calcination process. The obtained binder‐free 3D CuO NWs@Co3O4 nanostructures were further characterized by using X‐ray diffraction, X‐ray photoelectron spectroscopy, field‐emission scanning electron microscopy, and transmission electron microscopy. Furthermore, electrochemical sensing of glucose was studied by using Cyclic Voltammetry, and chronoamperometry techniques. Interestingly, 3D CuO NWs@Co3O4 electrode exhibits excellent performance for the oxidation of glucose compared with individual entities. The proposed sensor shows wide linear ranges from 0.5 μM to 0.1 mM with the sensitivity of 6082 μA/μM and the lowest detection limit (LOD) of 0.23 μM was observed with the signal to noise ratio, (S/N) of 3. The superior catalytic oxidation of glucose mainly is endorsed by the excellent electrical conductivity and synergistic effect of the Co3O4 and CuO NWs.

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“…[1][2][3] Its versatility, simplied optical setup, low background signals, high sensitivity and fast sample analysis abilities endow ECL with many advantages from an analytical perspective. [4][5][6] For semiconducting materials, ECL emission is caused by electronhole recombination. Theoretically, tuning the recombination dynamics of electrons and holes can modulate the nal ECL performance.…”

Section: Introductionmentioning

confidence: 99%

Modulating the electronic structure of a semiconductor to optimize its electrochemiluminescence performance

et al. 2019

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Macroporous graphene capped Fe3O4 for amplified electrochemiluminescence immunosensing of carcinoembryonic antigen detection based on CeO2@TiO2

Cited by 105 publications

References 30 publications

A Sensitive Photoelectrochemical Aptasensor for miRNA‐21 Based on the Sensitization Effect of CdSe Quantum Dots

A Sensitive Photoelectrochemical Aptasensor for miRNA‐21 Based on the Sensitization Effect of CdSe Quantum Dots

Fabrication of Hierarchically Structured MOF‐Co₃O₄ on Well‐aligned CuO Nanowire with an Enhanced Electrocatalytic Property

Modulating the electronic structure of a semiconductor to optimize its electrochemiluminescence performance

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Macroporous graphene capped Fe3O4 for amplified electrochemiluminescence immunosensing of carcinoembryonic antigen detection based on CeO2@TiO2

Cited by 105 publications

References 30 publications

A Sensitive Photoelectrochemical Aptasensor for miRNA‐21 Based on the Sensitization Effect of CdSe Quantum Dots

A Sensitive Photoelectrochemical Aptasensor for miRNA‐21 Based on the Sensitization Effect of CdSe Quantum Dots

Fabrication of Hierarchically Structured MOF‐Co3O4 on Well‐aligned CuO Nanowire with an Enhanced Electrocatalytic Property

Modulating the electronic structure of a semiconductor to optimize its electrochemiluminescence performance

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Fabrication of Hierarchically Structured MOF‐Co₃O₄ on Well‐aligned CuO Nanowire with an Enhanced Electrocatalytic Property