Macrophage-Targeting DNA Nanomaterials: A Future Direction of Biological Therapy
Yu-Chi Tu,
Yu-Mei Wang,
Li-Jun Yao
Abstract:DNA can be used for precise construction of complex and flexible micro-nanostructures, including DNA origami, frame nucleic acids, and DNA hydrogels. DNA nanomaterials have good biocompatibility and can enter macrophages via scavenger receptormediated endocytosis. DNA nanomaterials can be uniquely and flexibly designed to ensure efficient uptake by macrophages, which represents a novel strategy to regulate macrophage function. With the development of nanotechnology, major advances have been made in the design … Show more
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