Macrophage Polarization and Functions in Pathogenesis of Chronic Obstructive Pulmonary Disease
Gun-Dong Kim,
Eun Yeong Lim,
Hee Soon Shin
Abstract:Chronic obstructive pulmonary disease (COPD), the major leading cause of mortality worldwide, is a progressive and irreversible respiratory condition characterized by peripheral airway and lung parenchymal inflammation, accompanied by fibrosis, emphysema, and airflow limitation, and has multiple etiologies, including genetic variance, air pollution, and repetitive exposure to harmful substances. However, the precise mechanisms underlying the pathogenesis of COPD have not been identified. Recent multiomics-base… Show more
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