Macrodactyly — options and outcomes

Abstract

We report the outcomes of 32 patients diagnosed with macrodactyly. The average age at presentation was 46 months and there was an equal distribution across the sexes, although there was a male predominance in the upper limb and female predominance in the lower limb. There were 20 cases of upper limb macrodactyly and 13 cases affecting the lower limb. Multiple digits were more commonly affected than isolated digits, with an average of 2.5 digits affected. Static disease required significantly fewer operations than progressive disease. The need for repeated procedures must be highlighted in cases of progressive macrodactyly. In the vast majority of cases the functional and cosmetic outcome is good, with good patient acceptance.

Surgical Treatment of Macrodactyly

“…1 Since its description by Von Klein in 1824, 2 there have been only a handful of case series describing the diagnosis and treatment of macrodactyly. As our understanding of the disease process of macrodactyly has evolved, treatment has become more proactive and simultaneously more complex.…”

Signature Genes in Macrodactyly through Transcriptome Network Analysis Reveal their Association of Lipid Metabolism

“…Macrodactyly has been known to have an incidence rate of 0.9% [8]. Hardwick et al described a male predominance (1 : 0.66) in the upper limb in their study [8]. Barsky also reported male predominance (32 : 25) in macrodactyly almost 50 years ago [7].…”

“…Macrodactyly has been known to have an incidence rate of 0.9% [8]. Hardwick et al described a male predominance (1 : 0.66) in the upper limb in their study [8].…”

Paediatric Orthopaedic Diagnosis

“…Static forms of gigantism are relatively easy to treat, while progressive forms can be exceedingly diffi cult to treat (Hardwicke et al 2013 ). …”