“…True macrodactyly was reported by Barsky [2] to be more common in the hands than in the feet, but in the Kalen et al series (the largest series reported in the Western hemisphere), no such difference was reported [3]. Also, Barsky [2] reported a higher incidence in males than in females while Kalen et al [3] reported an equal sex ratio in the cases involving the hands but significant male predominance in the pedal cases. Bilateral involvement is more common than unilateral [1] and multiple digit involvement occurs in 50% of cases [3].…”
Section: Discussionmentioning
confidence: 60%
“…True macrodactyly is differentiated into two types; the static variety or macrodactyly simplex congenita in which the enlarged digit is present at birth and does not increase disproportionately with growth, and the second variety, the progressive type or macrodystrophia lipomatosa progressiva, in which there is growth of the involved digit(s) which grow in size at a faster rate than expected from normal growth [1]. True macrodactyly was reported by Barsky [2] to be more common in the hands than in the feet, but in the Kalen et al series (the largest series reported in the Western hemisphere), no such difference was reported [3]. Also, Barsky [2] reported a higher incidence in males than in females while Kalen et al [3] reported an equal sex ratio in the cases involving the hands but significant male predominance in the pedal cases.…”
Section: Discussionmentioning
confidence: 94%
“…Also, Barsky [2] reported a higher incidence in males than in females while Kalen et al [3] reported an equal sex ratio in the cases involving the hands but significant male predominance in the pedal cases. Bilateral involvement is more common than unilateral [1] and multiple digit involvement occurs in 50% of cases [3]. When more than one digit is involved, they are usually adjacent and the order of frequency in the hands is the index finger followed by middle finger and thumb; the ring and little fingers are seldom affected [1].…”
Section: Discussionmentioning
confidence: 99%
“…Macrodactyly is not a familial disorder and is almost exclusively an isolated anomaly [3]. In the 167 cases reported in the literature, only one had known neurofibromatosis [3].…”
Section: Resultsmentioning
confidence: 99%
“…Increased size of the phalanges of involved digits is a primary feature of the anomaly with involvement of the metacarpals/metatarsals not always present [3].…”
“…True macrodactyly was reported by Barsky [2] to be more common in the hands than in the feet, but in the Kalen et al series (the largest series reported in the Western hemisphere), no such difference was reported [3]. Also, Barsky [2] reported a higher incidence in males than in females while Kalen et al [3] reported an equal sex ratio in the cases involving the hands but significant male predominance in the pedal cases. Bilateral involvement is more common than unilateral [1] and multiple digit involvement occurs in 50% of cases [3].…”
Section: Discussionmentioning
confidence: 60%
“…True macrodactyly is differentiated into two types; the static variety or macrodactyly simplex congenita in which the enlarged digit is present at birth and does not increase disproportionately with growth, and the second variety, the progressive type or macrodystrophia lipomatosa progressiva, in which there is growth of the involved digit(s) which grow in size at a faster rate than expected from normal growth [1]. True macrodactyly was reported by Barsky [2] to be more common in the hands than in the feet, but in the Kalen et al series (the largest series reported in the Western hemisphere), no such difference was reported [3]. Also, Barsky [2] reported a higher incidence in males than in females while Kalen et al [3] reported an equal sex ratio in the cases involving the hands but significant male predominance in the pedal cases.…”
Section: Discussionmentioning
confidence: 94%
“…Also, Barsky [2] reported a higher incidence in males than in females while Kalen et al [3] reported an equal sex ratio in the cases involving the hands but significant male predominance in the pedal cases. Bilateral involvement is more common than unilateral [1] and multiple digit involvement occurs in 50% of cases [3]. When more than one digit is involved, they are usually adjacent and the order of frequency in the hands is the index finger followed by middle finger and thumb; the ring and little fingers are seldom affected [1].…”
Section: Discussionmentioning
confidence: 99%
“…Macrodactyly is not a familial disorder and is almost exclusively an isolated anomaly [3]. In the 167 cases reported in the literature, only one had known neurofibromatosis [3].…”
Section: Resultsmentioning
confidence: 99%
“…Increased size of the phalanges of involved digits is a primary feature of the anomaly with involvement of the metacarpals/metatarsals not always present [3].…”
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