Machine learning hypothesis-generation for patient stratification and target discovery in rare disease: our experience with Open Science in ALS
Joseph Geraci,
Ravi Bhargava,
Bessi Qorri
et al.
Abstract:IntroductionAdvances in machine learning (ML) methodologies, combined with multidisciplinary collaborations across biological and physical sciences, has the potential to propel drug discovery and development. Open Science fosters this collaboration by releasing datasets and methods into the public space; however, further education and widespread acceptance and adoption of Open Science approaches are necessary to tackle the plethora of known disease states.MotivationIn addition to providing much needed insights… Show more
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