Machine Learning-Assisted Classification of Paraffin-Embedded Brain Tumors with Raman Spectroscopy
Gilbert Georg Klamminger,
Laurent Mombaerts,
Françoise Kemp
et al.
Abstract:Raman spectroscopy (RS) has demonstrated its utility in neurooncological diagnostics, spanning from intraoperative tumor detection to the analysis of tissue samples peri- and postoperatively. In this study, we employed Raman spectroscopy (RS) to monitor alterations in the molecular vibrational characteristics of a broad range of formalin-fixed, paraffin-embedded (FFPE) intracranial neoplasms (including primary brain tumors and meningiomas, as well as brain metastases) and considered specific challenges when em… Show more
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