Abstract:Background HIV infection is the strongest single risk factor for the development of active tuberculosis (TB) in individuals with latent TB infection (LTBI). 1 NICE guidelines recommend screening HIV-positive patients for LTBI with an Interferon Gamma Release Assay (IGRA), plus a Tuberculin Skin Test (TST) in patients with a CD4 count <200 cells/mm 3 if IGRA negative. Method We began screening HIV-positive patients for LTBI in July 2011; this prospective study reports our 3 year data. Patients had an IGRA (T-SP… Show more
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