M1419: Endoscopy in the Elderly. Findings Justify Risks?

Tobal, Daniel; Tobal, Federico

doi:10.1016/j.gie.2010.03.419

Cited by 3 publications

(5 citation statements)

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“…Of the included studies, there were three randomized controlled studies, 37 prospective cohort studies, and 29 retrospective cohort studies. There were 35 studies from which data could be abstracted on patients over 65 6 13 19 23 31 32 33 34 35 47 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 and over 80 5 6 10 11 14 15 20 25 26 28 31 33 36 37 38 39 40 41 48 49 55 56 57 60 64 66 67 69 71 75 76 77 78 79 80 in which 10 286 and 4036 ERCPs had been performed, respectively; 19 studies were available from which data could be abstracted on patients over 9...…”

Section: Resultsmentioning

confidence: 99%

“…The lowest adverse event incidence rates in octogenarians were for perforation and cholangitis, while cardiopulmonary adverse events were the most frequently reported 10 11 14 15 25 28 31 33 36 38 40 48 49 55 60 64 66 67 69 75 76 77 83 . Additionally, the mortality rate was 6.1 deaths/1000 ERCPs (95 %CI 3.8 – 9.2) 5 10 11 14 15 20 25 26 28 31 33 36 37 38 40 41 48 49 55 56 57 60 64 66 67 69 75 76 77 78 79 83 , with 22 documented deaths among 32 of the studies involving octogenarians. Lastly, among patients ≥ 90, the most frequent adverse event was bleeding with an incidence rate of 28.6/1000 ERCPs (95 %CI 17.8 – 43.3) 10 11 17 20 24 27 42 43 44 45 46 50 ...…”

Section: Resultsmentioning

confidence: 99%

“…A statistically significant result was observed with a 95 %CI and a P value < 0.05. Not all studies used for incidence rate calculations were included in the meta-analysis because some studies did not have a younger age group with which to make a comparison 14 17 19 23 24 27 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 .…”

Section: Patients/materials and Methodsmentioning

confidence: 99%

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Adverse events in older patients undergoing ERCP: a systematic review and meta-analysis

Day

Lin

Somsouk

2014

EIO

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Background and study aims: Biliary and pancreatic diseases are common in the elderly; however, few studies have addressed the occurrence of adverse events in elderly patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). Our objective was to determine the incidence rates of specific adverse events in this group and calculate incidence rate ratios (IRRs) for selected comparison groups. Patients and methods: Bibliographical searches were conducted in Medline, EMBASE, and Cochrane library databases. The studies included documented the incidence of adverse events (perforation, pancreatitis, bleeding, cholangitis, cardiopulmonary adverse events, mortality) in patients aged ≥ 65 who underwent ERCP. Pooled incidence rates were calculated for each reported adverse event and IRRs were determined for available comparison groups. A parallel analysis was performed in patients aged ≥ 80 and ≥ 90. Results: Our literature search yielded 7429 articles, of which 69 studies met our inclusion criteria. Pooled incidence rates for adverse events (per 1000 ERCPs) in patients aged ≥ 65 were as follows: perforation 3.8 (95 %CI 1.8 – 7.0), pancreatitis 13.1 (95 %CI 11.0 – 15.5), bleeding 7.7 (95 %CI 5.7 – 10.1), cholangitis 16.1 (95 %CI 11.7 – 21.7), cardiopulmonary events 3.7 (95 %CI 1.5 – 7.6), and death 7.1 (95 %CI 5.2 – 9.4). Patients ≥ 65 had lower rates of pancreatitis (IRR 0.3, 95 %CI 0.3 – 0.4) compared with younger patients. Octogenarians had higher rates of death (IRR 2.4, 95 %CI 1.3 – 4.5) compared with younger patients, whereas nonagenarians had increased rates of bleeding (IRR 2.4, 95 %CI 1.1 – 5.2), cardiopulmonary events (IRR 3.7, 95 %CI 1.0 – 13.9), and death (IRR 3.8, 95 %CI 1.0 – 14.4). Conclusions ERCP appears to be safe in elderly patients, except in the very elderly who are at higher risk of some adverse events. These data on adverse event rates can help to inform clinical decision-making, the consent process, and comparative effectiveness analyses.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Patients/materials and Methodsmentioning

confidence: 99%

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Adverse events in older patients undergoing ERCP: a systematic review and meta-analysis

Day

Lin

Somsouk

2014

EIO

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“…First, as demographics shift towards an aging population, colonoscopies in the elderly are increasing, but the risk of the procedure, the discomfort due to bowel preparation, and the expected clinical benefits remain unclear. These factors were addressed for advanced endoscopic procedures (including colonoscopy) in a study in patients > 80 years old [130]. In a 2-year period, 375 / 5598 endoscopies (6.7 %) were performed in elderly patients.…”

Section: Colonoscopy Topics !mentioning

confidence: 99%

UEGW 2010 Report. Putting endoscopy into perspective

Papanikolaou¹,

Rösch²

2011

Endoscopy

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The 18th United European Gastroenterology Week (UEGW), held in Barcelona in October 2010, marked a return to the traditional "stand-alone" UEGW meeting after the previous year's combined congress format of GASTRO 2009. Various abstracts on endoscopic subjects were presented, providing a unique opportunity for those interested in gastrointestinal endoscopy to not only become acquainted with the latest advancements and research in the field, but also to meet and exchange experiences with colleagues from all over the world. This report will focus mainly on oral presentations, with a few selected poster presentations, which will be reviewed briefly in the context of recent literature in the respective fields of gastrointestinal endoscopy.

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“…Das Risiko der Prozedur, die Unannehmlichkeiten der Darmreinigung sowie der erwartete klinische Nutzen sind unklar. Diese Faktoren wurden in einer Studie mit anspruchsvollen endoskopischen Prozeduren einschließlich der Koloskopie an Patienten > 80 Jahre[130] untersucht. In einer Zwei-Jahres-Periode wurden 375 von 5598 Endoskopien (6,7 %) bei alten Patienten durchgeführt.…”

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Perspektiven der Endoskopie: Bericht von der UEGW 2010

Papanikolaou¹,

Rösch²

2011

Endo heute

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Übersicht 93 Endoskopische Resektionen und andere endotherapeutische Techniken ! Papanikolaou S, Rösch T. Perspektiven der Endoskopie … Endo heute 2011; 24: 93-108 Heruntergeladen von: University of British Columbia. Urheberrechtlich geschützt. Übersicht 95 Papanikolaou S, Rösch T. Perspektiven der Endoskopie … Endo heute 2011; 24: 93-108 Heruntergeladen von: University of British Columbia. Urheberrechtlich geschützt. Übersicht 97 Papanikolaou S, Rösch T. Perspektiven der Endoskopie … Endo heute 2011; 24: 93-108Heruntergeladen von: University of British Columbia. Urheberrechtlich geschützt.

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M1419: Endoscopy in the Elderly. Findings Justify Risks?

Cited by 3 publications

References 0 publications

Adverse events in older patients undergoing ERCP: a systematic review and meta-analysis

Adverse events in older patients undergoing ERCP: a systematic review and meta-analysis

UEGW 2010 Report. Putting endoscopy into perspective

Perspektiven der Endoskopie: Bericht von der UEGW 2010

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