LYZ2-SH3b as a novel and efficient enzybiotic against methicillin-resistant Staphylococcus aureus
Marzieh Asadi,
Mortaza Taheri-Anganeh,
Maryam Ranjbar
et al.
Abstract:Background
Enzybiotics are promising alternatives to conventional antibiotics for drug-resistant infections. Exolysins, as a class of enzybiotics, show antibacterial effects against methicillin-resistant Staphylococcus aureus (MRSA). This study evaluated a novel exolysin containing an SH3b domain for its antibacterial activity against MRSA.
Methods
This study designed a chimeric exolysin by fusing the Cell-binding domain (SH3b) from Lysostaphin wit… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.