Lysozyme distribution in healthy human skin

Papini, Manuela; Simonetti, S.; Franceschini, S. do C. C.; Scaringi, Lucia; Binazzi, M

doi:10.1007/bf00510410

Cited by 31 publications

(23 citation statements)

References 3 publications

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“…The results of the present investigation seem to confirm the values of lysozyme activity in serum and skin in normoglycemic subjects reported previously [1,2]. Furthermore, serum lysozyme activity in untreated diabetics does not differ significantly from that encountered in normoglycemics, while the lysozyme activity in the skin is significantly reduced (P < 0.01) in manifest diabetes, but not in subjects with only reduced glucose tolerance [1].…”

supporting

confidence: 91%

Erratum

1983

Arch Dermatol Res

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supporting

confidence: 91%

Erratum

1983

Arch Dermatol Res

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“…Moreover, some skin enzymes that has hydrolytic activity against chitosan, e.g. lysozyme, may enhance the scaffold biodegradability [16,17].…”

Section: Introductionmentioning

confidence: 99%

Nanofibrous poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/chitosan scaffolds for skin regeneration

Veleirinho¹,

Coelho²,

Dias³

et al. 2012

International Journal of Biological Macromolecules

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“…In skin lysozyme is mainly located in the cytoplasm of epidermal cells in granular layers and malpighian cells [12,15]. Pilosebaceous follicle cells and hair bulb cells as well as all parts of eccrine sweat glands were also positive for lysozyme.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial skin peptides and proteins

Schröder

Harder

2006

Cell. Mol. Life Sci.

223

216

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Human skin is permanently exposed to microorganisms, but rarely infected. One reason for this natural resistance might be the existence of a 'chemical barrier' consisting in constitutively and inducibly produced antimicrobial peptides and proteins (AMPs). Many of these AMPs can be induced in vitro by proinflammatory cytokines or bacteria. Apart from being expressed in vivo in inflammatory lesions, some AMPs are also focally expressed in skin in the absence of inflammation. This suggests that non-inflammatory stimuli of endogenous and/or exogenous origin can also stimulate AMP synthesis without inflammation. Such mediators might be ideal 'immune stimulants' to induce only the innate antimicrobial skin effector molecules without causing inflammation.

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Lysozyme distribution in healthy human skin

Cited by 31 publications

References 3 publications

Erratum

Erratum

Nanofibrous poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/chitosan scaffolds for skin regeneration

Antimicrobial skin peptides and proteins

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