Lysosomes and Homeostatic Regulation

Jacques, P. J.

doi:10.1002/9780470719695.ch12

Cited by 7 publications

(1 citation statement)

References 48 publications

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“…This fact is suggested both by a typical three-layered mem brane forming the vacuolar wall and by the absence of peculiarly lumines cent rickettsial antigen in the wall and in the liquid contents. At present, lysosomes, nonlysosomal secretory granules, phagosomes and vesicles participating in vesicular transportation are referred to as exoplasmic apparatus [Jacques, 1969], Therefore, it seems feasible to consider CBcontaining vacuoles to be formed from phagolysosomes. At a first stage of development, CB-containing phagosomes are transformed into common phagolysosomes.…”

Section: Discussionmentioning

confidence: 99%

Interaction between <i>Coxiellae burnetii </i>and the Cells in Experimental Q-Rickettsiosis

Ариэль¹,

Khavkin²,

Amosenkova³

1973

Pathobiology

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Lungs and spleens of white mice were examined after intranasal and intraperitoneal challenge with Coxiellae burnetii, respectively. As a rule, these organisms inhabit lung alveolar macrophages and spleen reticular cells’ vacuoles and are surrounded with a three-layered wall. The vacuoles seem to be formed from phagolysosomes. They are stable structures. When lodged within vacuoles for a long time, Coxiellae preserve viability. Due to the capacity of Coxiellae to parasitize in cellular phagolysosomes, one might consider Q-rickettsiosis as an ‘exoplasmic parasitosis’.

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Section: Discussionmentioning

confidence: 99%