Lyotropic model membrane structures of hydrated DPPC: DSC and small-angle X-ray scattering studies of phase transitions in the presence of membranotropic agents

Bulavin, L. A.; Soloviov, Dmytro; Gordeliy, Valentin; Svechnikova, O.S.; Krasnikova, A. O.; Kasian, N. A.; Vashchenko, O. V.; Lisetski, L. N.

doi:10.1080/01411594.2014.1002784

Cited by 11 publications

(8 citation statements)

References 31 publications

(18 reference statements)

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“…The main transition temperatures (T m ) of −17℃ and 42.1℃, respectively for DOPC and DPPC are consistent with the previously reported values 3,14,34,35) . The large difference in T m of the two PCs is due to the loose packing of the cis-hydrocarbon chains in DOPC bilayers compared to the all-trans chains in DPPC.…”

Section: Phase Transitionsupporting

confidence: 92%

Impact of Doping a Phytosteryl Sulfate on the Properties of Liposomes Made of Saturated and Unsaturated Phosphatidylcholines

et al. 2021

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aqueous core of liposomes and transported into the body. Similarly, lipophilic drugs are loaded in liposome s hydrophobic tail region. Biocompatibility of phospholipids makes them a popular choice for using in DDS. They are also used in skincare cosmetics 8,9) .Steroids constitute a class of organic compounds possessing a characteristic arrangement of four fused ring systems. The members of this family having an -OH functional group are called sterols. Among numerous steroids found in organisms, cholesterol in animals and phytosterols in plants serve as important constituents in biomembranes 10,11) . Cholesterol sulfate is also present in various animal tissues 12,13) . The major function of sterols in the membrane is to optimize its fluidity and permeability. By locating themselves between phospholipid molecules in the membrane, sterols can fluidize the membrane if it is initially in a gel phase and rigidify if it is in the liquid crystalline phase 14−16) . In liposomes too, sterols are used to achieve

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Section: Phase Transitionsupporting

confidence: 92%

Impact of Doping a Phytosteryl Sulfate on the Properties of Liposomes Made of Saturated and Unsaturated Phosphatidylcholines

et al. 2021

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“…The origin of defects in membranes was analyzed in works [10][11][12][13][14]. Aqueous solutions of membrane suspensions were studied using the methods of smallangle neutron and x-ray scattering and the − − method.…”

Section: Membrane Defects and Membrane Fusionmentioning

confidence: 99%

Medical Physics: Molecular Aspects

et al. 2015

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Actual problems in medical physics have been considered. Features in the cell membrane structure promoting the action of anticancer drugs are studied. The mechanism of an invasive method for measuring the blood pressure is analyzed. The tension distribution in the left ventricle wall was calculated. Conditions that prevent magnetic particles, nanodiamonds, and fullerene molecules, which are used to transport drugs in human body, to aggregate in liquid systems are determined. A molecular mechanism of electric welding of biological tissues has been proposed, as well as a method to study the surface of biological structures, by using ultrasound. The origin of structural changes in human hair under the influence of chemicals is determined. K e y w o r d s: cellular membranes, arterial pressure, cardiac muscle tension, drug transport, electric welding of biological tissues.

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“…Lipid membranes are an important component of living organisms, because they regulate plenty of the processes that are required to maintain the viability of every cell and cell organelles. That is why a considerable number of works on biophysics is devoted to the study of phase transitions in lipid membranes and their dependence on the temperature and pressure [1][2][3][4], the structural characteristics of various lipid phases [5,6], the influence of various impurities on the properties of membranes [7][8][9][10][11], as well as to the measurement of the dynamic characteristics of singleand multicomponent membranes [12,13].…”

Section: Introductionmentioning

confidence: 99%

Influence of Cholesterol Concentration on Bacteriorhodopsin Photocycle

et al. 2020

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The photocycle of the membrane protein bacteriorhodopsin in Dipalmitoylphosphatidylcholine(DPPC)/Cholesterol membranes with various cholesterol concentrations has been studied using the time-resolved spectroscopy method. The temperature dependences of the rate constants of bacteriorhodopsin transitions between transient states are shown to satisfy the Eyring equation. It is proved that the growth of the cholesterol concentration in the DPPC membrane accelerates the bacteriorhodopsin photocycle.

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Lyotropic model membrane structures of hydrated DPPC: DSC and small-angle X-ray scattering studies of phase transitions in the presence of membranotropic agents

Abstract: International audienc

Cited by 11 publications

References 31 publications

Impact of Doping a Phytosteryl Sulfate on the Properties of Liposomes Made of Saturated and Unsaturated Phosphatidylcholines

Impact of Doping a Phytosteryl Sulfate on the Properties of Liposomes Made of Saturated and Unsaturated Phosphatidylcholines

Medical Physics: Molecular Aspects

Influence of Cholesterol Concentration on Bacteriorhodopsin Photocycle

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