Lymphoscintigraphic Mapping in Melanoma and Breast Cancer

Young, M.

doi:10.2967/jnmt.120.246918

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…Since the introduction of breast lymphoscintigraphy, various techniques have been used, including intratumor and peritumor injection, subcutaneous or intradermal injection to the quadrant of the breast where the tumor is located, or combinations of injection techniques (3,4). The periareolar injection technique is simple, with a high success rate in sentinel lymph node detection (5).…”

Section: Discussionmentioning

confidence: 99%

A Practical Technique to Improve Visualization of Sentinel Nodes in the Axillary Region on Breast Lymphoscintigraphy: Medial Breast Traction by Patient

Özdemir

Corner

Searcy

et al. 2021

J. Nucl. Med. Technol.

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Methods: A standard method of performing breast lymphoscintigraphy is to obtain anterior and lateral views after periareolar intradermal injection of a radiotracer. However, a sentinel lymph node may be obscured by the activity at the injection site, especially on anterior views. Also, breast tissue may cause attenuation to prevent sentinel node visualization. In cases in which a sentinel lymph node is visualized on one view but not the other view or a sentinel lymph node is either not visualized or inadequately visualized, we repeat anterior and lateral views during medial traction of the breast performed by the patient. Results: We have found the medial breast traction technique performed by the patient to be especially useful for identification of axillary sentinel nodes. Conclusion: Repeat images during medial traction of the breast by the patient is an effective technique to improve visualization of sentinel lymph nodes in the axillary region.

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Section: Discussionmentioning

confidence: 99%

A Practical Technique to Improve Visualization of Sentinel Nodes in the Axillary Region on Breast Lymphoscintigraphy: Medial Breast Traction by Patient

Özdemir

Corner

Searcy

et al. 2021

J. Nucl. Med. Technol.

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“…Sentinel node metastasis was identified at histology. Sentinel node lymphoscintigraphy and radioguided surgery is a well-established technique for excisional biopsy of sentinel lymph nodes in patients with melanoma 1–8 . Melanoma below the knee has lymphatic drainage to the nodes in the popliteal fossa or inguinal region 9 .…”

mentioning

confidence: 99%

“…Sentinel node lymphoscintigraphy and radioguided surgery is a well-established technique for excisional biopsy of sentinel lymph nodes in patients with melanoma. [1][2][3][4][5][6][7][8] Melanoma below the knee has lymphatic drainage to the nodes in the popliteal fossa or inguinal region. 9 Because of the difference in patient positioning and anesthesia during surgery, preoperative localization is important for sentinel node biopsy even with the use of intraoperative γ probe.…”

mentioning

confidence: 99%

The Importance of SPECT/CT in Preoperative Localization of Sentinel Lymph Nodes in 2 Patients With Acral Melanoma in the Foot

Zhang

Zhu

Hua³

et al. 2021

Clin Nucl Med

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A 68-year-old woman with melanoma in the left heel underwent sentinel node lymphoscintigraphy and radioguided biopsy. The sentinel node lymphoscintigraphy with SPECT/CT detected 3 foci of increased activity in the popliteal fossa and inguinal region. When coregistered to CT, the sentinel node was localized in the inguinal region, and the popliteal foci were considered tracer retention in lymphatic vessel. In another patient with melanoma in the foot, sentinel node lymphoscintigraphy detected 3 foci of increased activity in the popliteal fossa and inguinal region, which were all identified to be nodal uptake in SPECT/CT. The sentinel node was finally localized in popliteal fossa in this patient.

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More than Just Skin-Deep: A Review of Imaging’s Role in Guiding CAR T-Cell Therapy for Advanced Melanoma

et al. 2023

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Advanced melanoma is one of the deadliest cancers, owing to its invasiveness and its propensity to develop resistance to therapy. Surgery remains the first-line treatment for early-stage tumors but is often not an option for advanced-stage melanoma. Chemotherapy carries a poor prognosis, and despite advances in targeted therapy, the cancer can develop resistance. CAR T-cell therapy has demonstrated great success against hematological cancers, and clinical trials are deploying it against advanced melanoma. Though melanoma remains a challenging disease to treat, radiology will play an increasing role in monitoring both the CAR T-cells and response to therapy. We review the current imaging techniques for advanced melanoma, as well as novel PET tracers and radiomics, in order to guide CAR T-cell therapy and manage potential adverse events.

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Lymphoscintigraphic Mapping in Melanoma and Breast Cancer

Cited by 3 publications

References 6 publications

A Practical Technique to Improve Visualization of Sentinel Nodes in the Axillary Region on Breast Lymphoscintigraphy: Medial Breast Traction by Patient

A Practical Technique to Improve Visualization of Sentinel Nodes in the Axillary Region on Breast Lymphoscintigraphy: Medial Breast Traction by Patient

The Importance of SPECT/CT in Preoperative Localization of Sentinel Lymph Nodes in 2 Patients With Acral Melanoma in the Foot

More than Just Skin-Deep: A Review of Imaging’s Role in Guiding CAR T-Cell Therapy for Advanced Melanoma

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