Lymphoplasmacytic lymphoma of the larynx, soft palate and nasal cavity

Bickerton, R C; Brockbank, M. J.

doi:10.1017/s0022215100105377

Cited by 8 publications

(10 citation statements)

References 7 publications

(8 reference statements)

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“…In our case, there was a pathologic feature of a diffuse infiltrate of plasmacytoid lymphocytes, which remained after radiotherapy. Bickerton and Brockbank (1988) also reported one radioresistant case of the same histology. In general, the maturity of tumour cells is one of the factors that influence radiosensitivity.…”

Section: Discussionmentioning

confidence: 84%

Primary non-Hodgkin's lymphoma of the larynx

et al. 1997

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Three cases of primary non-Hodgkin's lymphoma of the larynx are described. Histologically, two tumours belonged to the category of low grade B-cell lymphomas of the small cell type (extranodal marginal zone B-cell lymphoma and lymphoplasmacytoid lymphoma), and the third was classified as a peripheral T-cell lymphoma of unspecified type. The clinical stage was IE in two cases, and IV in another case. In two cases, complete remission was obtained with radical radiotherapy. But in the other case, which was histologically lymphoplasmacytoid lymphoma, the response to radiotherapy was poor, and surgery was required. There was no relapse subsequent to treatment. Primary non-Hodgkin's lymphoma of the larynx is rare. Several reported cases have clinical features similar to those of MALT-type lymphomas arising in other extranodal sites. Although most of the reported cases have been cured with radiotherapy, in some cases dissemination to other extranodal sites may occur. Therefore careful periodic evaluation is imperative.

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Section: Discussionmentioning

confidence: 84%

Primary non-Hodgkin's lymphoma of the larynx

et al. 1997

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“…The LPL subtype is even more uncommon, with only three prior reports of it in the literature involving the larynx specifically [7][8][9]. Patients often present with non-specific symptoms of the larynx, including dysphonia, dysphagia, dyspnea, and globus sensation [2].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Laryngeal Non-IgM Lymphoplasmacytic Lymphoma

Hong¹,

Han²,

Shiba³

2022

Cureus

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Laryngeal lymphoplasmacytic lymphoma has been previously reported only a handful of times in the literature. It can be difficult to diagnose without significant histologic workup and proper methodology.Here, we demonstrate the first known case of laryngeal lymphoplasmacytic lymphoma with nonimmunoglobulin M (IgM) features. In this case report, a 79-year-old female with seropositive rheumatoid arthritis presented with five months of dysphonia and dyspnea on exertion. Lab studies revealed high levels of serum IgA and IgG. Flexible laryngoscopy and computed tomography of the neck showed a left supraglottic submucosal mass, which was surgically excised with a carbon dioxide laser. The histology of the mass confirmed the diagnosis of lymphoplasmacytic lymphoma. The patient was treated with 30.6 Gy of radiation therapy and eight cycles of rituximab with successful remission of her lymphoma and no evidence of disease recurrence six months after treatment completion. Lymphoplasmacytic lymphoma without corresponding IgM gammopathy is unusual and has been shown to have a higher frequency of extramedullary involvement. This is the first known manifestation of non-IgM lymphoplasmacytic lymphoma in the larynx.

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“…There are limited case reports in the literature [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23].…”

Section: Discussionmentioning

confidence: 99%

Upper Aero-Digestive Tract Lymphomas Presenting as Polypoidal/Pedunculated Lesions: Case Report and Review of Literature

Akhtar

Rana

Aldei

et al. 2013

Head and Neck Pathol

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Aim To describe a case of diffuse large B cell lymphoma (DLBCL) presenting as a pedunculated/polypoidal mass in upper aero-digestive tract and to review pertinent literature. Methods Using Pubmed advanced search, case reports and literature were reviewed for this condition.Results A 16 year old female presented with history of shortness of breath when lying down, voice change, progressing odynophagia and feeling of throat lump. Direct visualization showed flower like pedunculated mass, attached to the left lateral oropharyngeal wall. Excision of this mass showed DLBCL and no disease anywhere. She received four cycles of Rituximab ? CHOP and is diseasefree for 4 years. Only 21 cases of pedunculated upper aerodigestive tract lymphomas have been reported in literature. Median age 53 years (16-90 years), males 80 %, females 20 %, localized disease (65 %). Common sites were endobronchial polypoid lesion (7 cases), nasal polyps (7), nasopharyngeal polyps (2), nose and paranasal sinus (1), laryngeal polyp (2) and one each as gum, esophagus and oropharyngeal (current case) polyp. Pathology showed aggressive lymphoma in 94 %. Conclusion DLBCL as an extranodal pedunculated lesion in the oropharynx is very rare. Careful pathological evaluation is essential for these lesions for proper diagnosis.

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Lymphoplasmacytic lymphoma of the larynx, soft palate and nasal cavity

Cited by 8 publications

References 7 publications

Primary non-Hodgkin's lymphoma of the larynx

Primary non-Hodgkin's lymphoma of the larynx

A Rare Case of Laryngeal Non-IgM Lymphoplasmacytic Lymphoma

Upper Aero-Digestive Tract Lymphomas Presenting as Polypoidal/Pedunculated Lesions: Case Report and Review of Literature

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