Lymphoma Involving the Ulnar Nerve

Choi, A. Lam; Koh, Sung Hye; Jun, Sun-Young; Hwang, Hee Sung; Cho, Hye Won; Jang, Kyung Mi; Jeon, Eui Yong; Lee, Hyun; Lee, In Jae

doi:10.7863/jum.2008.27.10.1527

Cited by 9 publications

(6 citation statements)

References 6 publications

(4 reference statements)

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“…Ultrasound has been described as useful non-invasive, highly sensitive but with low-specificity tool for identifying peripheral nerve involvement in B-cell lymphoma. 72 Nerve infiltration and malignant neovascularization might be detected as focal nerve enlargement and increased vascularization in Doppler sonography, thus helping identify a favorable site for nerve biopsy. 73 Nerve biopsy allows the visualization and characterization of the malignant cells and remains the diagnostic gold standard.…”

Section: Neurolymphomatosismentioning

confidence: 99%

Peripheral nervous system involvement in lymphomas

Briani

Visentin

Campagnolo

et al. 2019

J Peripheral Nervous Sys

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The peripheral nervous system may be involved at any stage in the course of lymphoproliferative diseases. The different underlying mechanisms include neurotoxicity secondary to chemotherapy, direct nerve infiltration (neurolymphomatosis), infections, immune‐mediated, paraneoplastic or metabolic processes and nutritional deficiencies. Accordingly, the clinical features are heterogeneous and depend on the localization of the damage (ganglia, roots, plexi, and peripheral nerves) and on the involved structures (myelin, axon, and cell body). Some clinical findings, such a focal or diffuse involvement, symmetric or asymmetric pattern, presence of pain may point to the correct diagnosis. Besides a thorough medical history and neurological examination, neurophysiological studies, cerebrospinal fluid analysis, nerve biopsy (in selected patients with suspected lymphomatous infiltration) and neuroimaging techniques (magnetic resonance neurography and nerve ultrasound) may be crucial for a proper diagnostic workup.

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Section: Neurolymphomatosismentioning

confidence: 99%

Peripheral nervous system involvement in lymphomas

Briani

Visentin

Campagnolo

et al. 2019

J Peripheral Nervous Sys

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“…There were a few case reports about tumors of the ulnar nerve at the elbow, including intraneural hemangioma,44 lymphoma,45 infiltration of myeloma cells,46 intraneural perineurioma,47 capillary hemangioma,48 or neurinoma 49…”

Section: Ultrasonography and Underlying Abnormalities In Unementioning

confidence: 99%

Ultrasonography in ulnar neuropathy at the elbow: A critical review

2011

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“…Ultrasound provided diagnostic clarity in this case by elucidating the variant anatomical path of the median nerve thus providing an explanation for the aberrant NCS, by prompting more accurate stimulation over the actual course of the median nerve, and by excluding other obvious nerve pathology suggestive of an inflammatory or infiltrative process. 6,[8][9][10][11] Ultrasound can identify multifocal areas of nerve compression associated with immunemediated neuropathies. [10][11][12] Neurolymphomatosis may appear on ultrasound as diffuse or nodular nerve thickening or as discrete or heterogenous hypoechoic or anechoic masses which may appear almost cyst like.…”

Section: Discussionmentioning

confidence: 99%

Variant Median Nerve Anatomy: Ultrasound Evidence of a Pseudoconduction Block

Abrams

Pedowitz²,

Simpson³

et al. 2021

Journal of Clinical Neuromuscular Disease

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Introduction:A conduction block at a noncompressible site warrants further investigation. Methods and materials:A 36-year-old woman with a history of Hodgkin lymphoma and chemotherapy-induced polyneuropathy developed bilateral hand numbness and paresthesias. Workup revealed bilateral carpal tunnel syndrome and an apparent superimposed conduction block of the median nerve in the forearm. Given the history of cancer, there was concern for an infiltrative or an immune-mediated process. Results:Neuromuscular ultrasound demonstrated that the median nerve descended the upper extremity along an atypical path, deep along the posteromedial aspect of the upper arm, and relatively medially in the forearm. Ultrasound-directed nerve stimulation revealed there was no conduction block. This anatomical variant has been rarely described and has not been reported previously to mimic conduction block or been documented via ultrasound. Conclusions:This case demonstrates that neuromuscular ultrasound may supplement the electrodiagnostic study and limit confounding technical factors because of rare anatomic variation.

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Lymphoma Involving the Ulnar Nerve

Cited by 9 publications

References 6 publications

Peripheral nervous system involvement in lymphomas

Peripheral nervous system involvement in lymphomas

Ultrasonography in ulnar neuropathy at the elbow: A critical review

Variant Median Nerve Anatomy: Ultrasound Evidence of a Pseudoconduction Block

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