Lymphoid hyperplasia of the bowel and its surgical significance in children

Acute Appendicitis: Are we Over Diagnosing it?

“…Lymphoid hyperplasia has been noted to occur in up to 25% of patients with acute appendicitis 8 and appendicectomy in patients having just lymphoid hyperplasia on histology has been seen to relieve pain. 1,2,9 In our study, pinworm was found to occur in teenage children both with and without evidence of acute appendicitis. Pinworm has been reported to occur on histology in some large series ranging from 1.4-4.1%, [10][11][12] with evidence to suggest that it may be the cause of abdominal pain mimicking appendicitis without causing appendicitis.…”

Colonoscopic diagnosis of lymphoid hyperplasia causing recurrent intussusception: Report of a case

“…Both massive fibrosis and infiltration of the inflammatory cells were observed in the serosal layer, thus indicating chronic changes ( lymphoid tissue, such as Peyer's patches, within the intestinal wall to form a polypoid lesion such as that seen in the present case. [8][9][10] Although lymphoid hyperplasia is a non-specific hyperplastic change, it is very often caused by several kinds of infection. 7,8 Reported infective organisms associated with intussusception include adenovirus, 7,10-13 herpes simplex virus, 13 rotavirus, 14 echovirus, 11 Giardia, 9 etc.…”

“…[8][9][10] Although lymphoid hyperplasia is a non-specific hyperplastic change, it is very often caused by several kinds of infection. 7,8 Reported infective organisms associated with intussusception include adenovirus, 7,10-13 herpes simplex virus, 13 rotavirus, 14 echovirus, 11 Giardia, 9 etc. The patient in the present case developed diarrhea at the first episode of intussusception and also showed reactive hyperplasia of the 5).…”

“…In children over 2 years of age, lymphoid hyperplasia caused by persistent infection has been recognized as a distinctive and rather rare causative factor in the development of intussusception as well as other organic lesions. 8,[16][17][18] Considering the natural course and the required treatment, lymphoid hyperplasia has been classified into acute and chronic forms by Jona et al 8 Although should thus be confirmed, because many patients undergo an unnecessary intestinal resection due to difficulty in ruling out malignancy or other diseases, 17 and the treatment varies with the patient's condition. Although a barium enema yields the diagnostic findings of a filling defect with a central dimpling, 9,11,19 differentiation from the other lesions, such as malignancy, is often difficult.…”

“…5,6 Lymphoid hyperplasia in the terminal ileum has also been reported to be a causative factor of intussusception. 7,8 We treated a 6-year-old boy who had recurrent ileocecal intussusception caused by focal lymphoid hyperplasia, which was diagnosed by colonoscopy before operation.…”