Lymphoepithelioma-like Carcinoma of the Breast Synchronous with a High-Grade Invasive Ductal Carcinoma and Ductal Carcinoma in Situ in a Different Quadrant of the Same Breast: A Case Report

Abstract

Lymphoepithelioma-like breast carcinoma (LELC) is a rare type of malignant breast tumor that is not included in the current edition of the World Health Organization (WHO) classification of breast tumors. Currently, there are no clearly defined therapeutic strategies, and the general information on breast LELC is based on sporadic clinical cases described in the medical literature. We present a clinical case that describes a 49-year-old woman with a tumor formation in the right breast, histologically verified as LELC, together with a non-palpable, synchronous high-grade invasive ductal carcinoma and ductal carcinoma in situ Grade 2 (DCIS G2) in a different quadrant of the same breast. To our knowledge, this is the first case described in the literature that combines a LELC with a synchronous carcinoma in the same breast.

Recent Advances in Breast Cancer Diagnosis, Treatment, Psychology, Management, and Reconstruction

“…Finally, the case report by Nanev et al [ 7 ] shows that despite all the advances in breast cancer research, there is still much to be discovered. Cases of lymphoepithelioma-like breast carcinoma (LELC) can be found in the literature, but there has not been a clearly defined treatment, much less an option for LELC occurring simultaneously with other carcinomas of the breast as is described in this case report.…”