Lymphoepithelial cysts of the pancreas: case report and review of the literature

Ciers, Philippe; Vanderhaeghe, Daphné; Vansteenkiste, Franky; Moubax, Kim; Vanooteghem, S; Vanneste, A.; Moerkercke, Wouter Van

doi:10.1080/00015458.2022.2050032

Cited by 1 publication

(1 citation statement)

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“…Histopathology: LECs are lined by squamous epithelium and surrounded by subepithelial lymphoid tissue with germinal centers [84,98]. Other rarer features of LECs include: containing sebaceous differentiation, keratin debris and cholesterol crystals, scattered mucinous cells with features similar to goblet cells, and multinucleated giant cells [84,[98][99][100][101]. Dermoid cysts can include mucinous epithelium, respiratory-type mucosa, sebaceous units, and hair.…”

Section: Squamous Lined Epithelial Cystsmentioning

confidence: 99%

Pancreatic Cystic Lesions: A Focused Review on Cyst Clinicopathological Features and Advanced Diagnostics

2022

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Macroscopic, endomicroscopic, and histologic findings and correlation are an integral part of the diagnostic evaluation of pancreatic cystic lesions (PCLs), as complementing morphologic features seen by different specialties are combined to contribute to a final diagnosis. However, malignancy risk stratification of PCLs with worrisome features can still be challenging even after endoscopic ultrasound guided-fine needle aspiration (EUS-FNA) with cytological evaluation. This review aims to summarize cyst clinicopathological features from the pathologists’ perspective, coupled with knowledge from advanced diagnostics–confocal laser endomicroscopy and cyst fluid molecular analysis, to demonstrate the state-of-art risk stratification of PCLs. This review includes illustrative photos of surgical specimens, endomicroscopic and histologic images, and a summary of cyst fluid molecular markers.

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