Lymphocytic Infiltration of the Skin Jessner-Kanof After Treatment With a Hydroquinone-Containing Bleaching Cream

Kérob, Delphine; Dupuy, Alain; Reygagne, P.; Levy, Amit; Morel, Patrice; Bernard, Bruno; Lebbe, Célèste

doi:10.1001/archderm.142.12.1656

Cited by 20 publications

(3 citation statements)

References 6 publications

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Section: Discussionmentioning

confidence: 99%

“…1,3,6 The other pattern of hypertrichosis depicting as facial area, cheeks and eyebrows hypertrichosis, including sometimes body trunk and extremities, is also in the literature presented. 1,3,6,7 Ears when presented with hair growth mimicking hairy pinnae have also been cited in two male cases due to EGFR inhibitor therapies. 8 In our case, bilateral ear's implication with hypertrichosis of lower pinnae, tragus, antitragus, helix and scaphoid fossae is an interesting firstly recorded female report raising considerable vision.…”

Section: Discussionmentioning

confidence: 99%

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Pinnae and facial hypertrichosis induced by cetuximab

Alexandris

Alevizopoulos

Palamaris

et al. 2022

J Oncol Pharm Pract

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Introduction Anti-EGFR targeted anti-cancer treatment is associated with various skin adverse events. Cetuximab is often associated with acneiform papules and skin disorders. Hypertrichosis cited in face pinnae and eyelash trichomegaly are seldom described. Case report A 72-year-old female cancer patient presented deteriorating facial-pinnae hypertrichosis and eyelash prolongation post cetuximab infusion. Management and outcome Consecutive cetuximab administration led to exaggerating hairy skin side effects, fully alleviated when the drug was discontinued. Discussion To the best of our knowledge, this is the first reported case of an anti-EGFR-associated diffuse pinnae hypertrichosis presentation in a female patient in literature. This distinct entity can be easily diagnosed and manipulated with early drug withdrawal. An extensive review of relevant basic molecular research is provided to increase physicians’ awareness.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pinnae and facial hypertrichosis induced by cetuximab

Alexandris

Alevizopoulos

Palamaris

et al. 2022

J Oncol Pharm Pract

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“…In addition to alopecia and texture/color changes, patients complain of slow scalp hair growth, facial hair growth [11] and trichomegaly [12]. In one case, gefitinib therapy resulted in striking terminal hair growth on the nose tip [13], whereas in a formerly bald patient hypertrichosis of the scalp, eyelashes and eyebrows occurred after cetuximab therapy [14].…”

Section: Discussionmentioning

confidence: 99%

Hairy Pinnae after Orchiectomy and Chemotherapy for Testicular Cancer: Acquired Localized Hypertrichosis of the Ears

Sanger¹,

Dietrich²,

Pelivani³

et al. 2011

Dermatology

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Acquired localized hypertrichosis has rarely been reported. Here, we describe a patient with localized hypertrichosis of the pinnae that occurred 4 months after orchiectomy and chemotherapy for a testicular carcinoma. To our knowledge, this is the first case of an acquired hypertrichosis of the pinnae after cancer therapy. We propose that in our patient either hypogonadism or the hormonal imbalance caused by the cancer therapy led to the development of the hairy pinnae, perhaps alongside a genetic predisposition for hairy ears.

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Acquired Disorders of Hair

Harries,

Holmes,

McMichael

et al. 2024

Rook's Textbook of Dermatology

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This chapter reviews acquired hair disorders, including common scarring and non‐scarring alopecia presentations, conditions characterised by excessive body hair growth and acquired hair shaft disorders. We also describe the biology of normal hair follicles, including structure, hair cycle control and immunity, to better understand the mechanisms underlying these conditions. We present methods for clinical assessment, recommended investigation and management of each disease, and present summaries of frequently used therapeutics and cosmetic options employed when treating these problems.

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Lymphocytic Infiltration of the Skin Jessner-Kanof After Treatment With a Hydroquinone-Containing Bleaching Cream

Cited by 20 publications

References 6 publications

Pinnae and facial hypertrichosis induced by cetuximab

Pinnae and facial hypertrichosis induced by cetuximab

Hairy Pinnae after Orchiectomy and Chemotherapy for Testicular Cancer: Acquired Localized Hypertrichosis of the Ears

Acquired Disorders of Hair

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