Lymphknotentuberkulose als Erstmanifestation eines Morbus Hodgkin

Audebert, Franz; Schneidewind, Arne; Hartmann, Pia; Kullmann, Frank; Schölmerich, Jürgen

doi:10.1007/s00063-006-1071-3

Cited by 12 publications

(3 citation statements)

References 22 publications

(26 reference statements)

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“…The presence of lymphoma and tuberculosis in the same patient has been reported in the literature [1,4,5]. Tuberculosis and lymphoma could represent a diagnostic challenge as they share many clinical and radiological features.…”

Section: Discussionmentioning

confidence: 55%

An Unusual Triad of Hemophagocytic Syndrome, Lymphoma and Tuberculosis in a Non-HIV Patient

et al. 2017

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Patient: Female, 58Final Diagnosis: Hemophagocytic syndrome • lymphoma and tuberculosis in a non-HIV patientSymptoms: Dizziness • feverMedication: —Clinical Procedure: —Specialty: Critical Care MedicineObjective:Rare co-existance of disease or pathologBackground:Lymphoma complicated with hemophagocytic syndrome and tuberculosis has been rarely reported. The clinical and radiological presentation of these potentially fatal conditions can be easily confused and there is a potential for misdiagnosis.Case Report:We present a 58-year-old Hispanic female who was admitted to the hospital with dizziness and fever. Her initial admission diagnosis was severe sepsis secondary to community acquired pneumonia. She was started on intravenous antibiotics. Due to mediastinal lymphadenopathy, lymphoma was considered as a differential diagnosis for which she underwent bronchoscopy and endobronchial ultrasound-guided sampling of her mediastinal lymph nodes. Lymph node aspirate was suggestive of lymphoma. Initial cultures were negative. Her clinical course was complicated with respiratory failure, cytopenia, and rapidly progressive cervical lymphadenopathy. The patient underwent cervical lymph node excision and bone marrow biopsy. The pathology of the lymph nodes confirmed T cell lymphoma, and bone marrow revealed hemophagocytosis. The patient was started on chemotherapy but she continued to deteriorate and died on day 20 of her hospital admission. Post-mortem results of cultures from a cervical lymph node biopsy and PCR were positive for Mycobacterium tuberculosis.Conclusions:We suggest an aggressive tissue diagnosis with staining for acid-fast bacilli for early diagnosis in patients presenting with hemophagocytic syndrome secondary to lymphoma as coexisting tuberculosis is a consideration. Tuberculosis re-activation should be considered in patients from an endemic region who present with lymphoma and a deteriorating clinical condition.

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Section: Discussionmentioning

confidence: 55%

An Unusual Triad of Hemophagocytic Syndrome, Lymphoma and Tuberculosis in a Non-HIV Patient

et al. 2017

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“…Not only that, although our patient initially received regular treatment for TB, he did not improve but worsened clinically. e case that stood out to us was about a 63-year-old woman who was admitted for suspected reactivation of lymph node tuberculosis previously treated successfully and diagnosed one year earlier [6].…”

Section: Discussionmentioning

confidence: 99%

Hodgkin Lymphoma Mimicking Lumbar Spine Tuberculosis

Djossou

Ghassem

Toufik

et al. 2022

Case Reports in Rheumatology

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Introduction. The clinical manifestations of Hodgkin lymphoma (HL) can closely mimic spine and lymph node tuberculosis (TB). Case Description. A 48-year-old man was initially treated for retroperitoneal lymph nodes TB, and this diagnosis was made without bacteriological and histopathological confirmation. After four months of regular therapy for TB, he did not improve and was admitted to our department for lumbar spine pain. We first made diagnosis of tuberculous spondylodiscitis, and anti-TB treatment was strengthened. But, after three weeks of hospitalization, his condition worsened clinically with onset of swelling of the left supraclavicular lymph node. So, after surgical excision and anatomopathological examination of the lymph node, the diagnosis of nodular sclerosis classic Hodgkin lymphoma was made. He was treated by chemotherapy, and his condition improved significantly after the first 2 cycles of chemotherapy. Conclusion. Repeated investigations may be helpful in establishing a correct diagnosis and starting an effective treatment in this highly curable disease.

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“…Moreover, differentiating between systemic lymph node TB and lymphoma is difficult because both diseases can lead to hypermetabolic lesions on 18 F-fluorodeoxyglucose positron emission tomography ( 18 F-FDG PET/CT) analysis. 3 , 4 This article reported a case of systemic lymph node TB mimicking lymphoma on 18 F-FDG PET/CT and presented several differential diagnosis criteria.…”

Section: Introductionmentioning

confidence: 99%