Lymphedema of the Hand and Forearm Following Fracture of the Distal Radius

Kasper, David A.; Meller, Menachem M.

doi:10.3928/01477447-20080201-14

Cited by 10 publications

(4 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…34 Damage to the radial artery has been noted in a number of cases. This is usually manifested as a direct tear of the vessel at the time of surgery 35,36 but latent pseudoaneursym, 37 arteriovenous fistula formation 38 and lymphoedema 39 have also been cited.…”

Section: Discussionmentioning

confidence: 99%

The cadaveric anatomy of the distal radius: implications for the use of volar plates

McCann

Clarke

Amirfeyz

et al. 2012

annals

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

The cadaveric anatomy of the distal radius: implications for the use of volar plates

McCann

Clarke

Amirfeyz

et al. 2012

annals

View full text Add to dashboard Cite

show abstract

“…The lymphatic system may be affected following closed traumatic upper limb or lower limb fractures or following surgery (e.g., shoulder arthroplasty). [40][41][42] Lymphoscintigraphy scans have shown an enlargement of lymphatics and lymph nodes that drain the site of injury or bone fracture (when the fracture heals without complications). Although the pathogenesis underlying the lymphatic response to a bone fracture is unclear, both clinical and experimental observations indicate that an inflammatory process triggered by invading bacteria or self-antigens exposed during trauma may lead to the persistent posttraumatic edema.…”

Section: Lymphedema Secondary To Podoconiosismentioning

confidence: 99%

Secondary lymphedema: Pathogenesis

Varghese¹

2021

JSSTD

View full text Add to dashboard Cite

Secondary lymphedema follows an acquired defect in the lymphatic system. The common causes leading to a defective lymphatic function include infection, inflammation, malignancy, trauma, obesity, immobility, and therapeutic interventions. Understanding the pathogenesis of lymphedema is of prime importance in offering effective treatment. The pathogenetic mechanisms such as lymphatic valvular insufficiency, obliteration/ disruption of lymphatic vessels, and decreased lymphatic contractility aggravate lymphatic hypertension and lymphstasis. Accumulation of lymph, interstitial fluid, proteins, and glycosaminoglycans within the skin and subcutaneous tissue eventually stimulates collagen production by fibroblasts, causes disruption of elastic fibers, and activates keratinocytes, fibroblasts, and adipocytes. These result in thickening of skin and cause fibrosis of subcutaneous tissue. However, the sequence of these pathomechanisms, their inter-relationship and progression vary depending on the specific etiology of the lymphedema. In this article, we discuss the possible cellular and molecular mechanisms involved in the pathogenesis. Further studies to delineate the exact sequence of pathogenic processes surrounding the primary triggering event can help to formulate tailored therapeutic approaches.

show abstract

“…The most common causes of lymphedema are surgical trauma such as lymph node dissection and radiation therapy (2). Additionally, although it rarely occurs, critical traumatic injury such as extensive burns and massive fractures can cause lymphedema, as described in previous case reports (3)(4)(5)(6)(7)(8)(9).…”

Section: Introductionmentioning

confidence: 98%