Lymphedema and Lymphocysts Following Lymphadenectomy May Be Prevented by Omentoplasty: A Pilot Study

Logmans, A.; Kruyt, R. H.; Bruin, Hein G. de; Cox, P. H.; Pillay, M.; Trimbos, J. Baptist

doi:10.1006/gyno.1999.5624

Cited by 61 publications

(37 citation statements)

References 15 publications

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“…However, the observed disparity is more likely a function of the observed heterogeneity among study methods (eg, assessment methods and length of followup) than it is of the particular characteristics of the solid tumors reviewed. Increased lymphedema risk was observed for patients undergoing pelvic dissections (22%), 18,23,26,30,[36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54] as well as for those undergoing radiation therapy (31%). 17,24,25,33,36-38,40,42,43,45,46,48,50-54 The high incidence of lymphedema observed for gynecological malignancies (20%) is not surprising given that approximately 70% of the patients in these studies were reported to have undergone pelvic lymph node dissections and/or radiation therapy.…”

Section: Discussionmentioning

confidence: 99%

Lymphedema beyond breast cancer

Cormier

Askew

Mungovan

et al. 2010

Cancer

398

170

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BACKGROUND: Secondary lymphedema is a debilitating, chronic, progressive condition that commonly occurs after the treatment of breast cancer. The purpose of the current study was to perform a systematic review and meta-analysis of the oncology-related literature excluding breast cancer to derive estimates of lymphedema incidence and to identify potential risk factors among various malignancies. METHODS: The authors systematically reviewed 3 major medical indices (MEDLINE, Cochrane Library databases, and Scopus) to identify studies that included a prospective assessment of lymphedema after cancer treatment. Studies were categorized according to malignancy, and data included treatment, complications, lymphedema measurement criteria, lymphedema incidence, and followup interval. A quality assessment of individual studies was performed using established criteria for systematic reviews. Bayesian meta-analytic techniques were applied to derive summary estimates when sufficient data were available. RESULTS: A total of 47 studies (7779 cancer survivors) met inclusion criteria: melanoma (n ¼ 15), gynecologic malignancies (n ¼ 22), genitourinary cancers (n ¼ 8), head/neck cancers (n ¼ 1), and sarcomas (n ¼ 1). The overall incidence of lymphedema was 15.5% and varied by malignancy (P < .001): melanoma, 16% (upper extremity, 5%; lower extremity, 28%); gynecologic, 20%; genitourinary, 10%; head/neck, 4%; and sarcoma, 30%. Increased lymphedema risk was also noted for patients undergoing pelvic dissections (22%) and radiation therapy (31%). Objective measurement methods and longer follow-up were both associated with increased lymphedema incidence. CONCLUSIONS: Lymphedema is a common condition affecting cancer survivors with various malignancies. The incidence of lymphedema is related to the type and extent of treatment, anatomic location, heterogeneity of assessment methods, and length of follow-up. Cancer 2010;116:5138-49.

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Section: Discussionmentioning

confidence: 99%

Lymphedema beyond breast cancer

Cormier

Askew

Mungovan

et al. 2010

Cancer

398

170

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“…However, more recent series have reported much lower incidences. Ilancheran et al noted an incidence of 25.3% in clinically diagnosable lymphocele with cervical cancer (2), Conte et al noted an incidence of 22% in cervical cancer (3), Logmans et al an incidence of 20~32% in gynecologic cancer (4) and Panici et al an incidence of 10~25% in gynecologic cancer (5). The reported incidences of lymphoceles following pelvic lymphadenectomy vary, which is probably related to the method of identification used.…”

Section: Introductionmentioning

confidence: 97%

An Analysis of the Risk Factors and Management of Lymphocele after Pelvic Lymphadenectomy in Patients with Gynecologic Malignancies

Kim

et al. 2004

Cancer Res Treat

111

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“…This resulted in detailed knowledge upon tumor spread and has proven essential for optimizing the individual treatment [7,15,16,25,30,31]. Due to minimal invasiveness compared to open surgery immediate radiotherapy or chemoradiation became possible shortly after surgery.…”

Section: Introductionmentioning

confidence: 99%