2024
DOI: 10.3390/ijms25052853
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Lymphatic System and the Kidney: From Lymphangiogenesis to Renal Inflammation and Fibrosis Development

Elodie Stasi,
Savino Sciascia,
Carla Naretto
et al.

Abstract: The lymphatic kidney system plays a crucial role in managing interstitial fluid removal, regulating fluid balance, and tuning immune response. It also assists in the reabsorption of proteins, electrolytes, cytokines, growth factors, and immune cells. Pathological conditions, including tissue damage, excessive interstitial fluid, high blood glucose levels, and inflammation, can initiate lymphangiogenesis—the formation of new lymphatic vessels. This process is associated with various kidney diseases, including p… Show more

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