Lymphatic drainage pathways from the cervix uteri: Implications for radical hysterectomy?

Long-term Pelvic Floor Function and Quality of Life After Radical Surgery for Cervical Cancer: A Multicenter Comparison Between Different Techniques for Radical Hysterectomy With Pelvic Lymphadenectomy

“…This model showed an extensive network of autonomic nerves in the vesicouterine ligament, it is in this particular region in which the WO technique is more radical. 33 Contrary to our findings, Sowa et al described that less radically treated women had a better physical and role function. However, this study compared a group without adjuvant RT with a group in which 31% of the women received adjuvant RT which may bias this study, especially since the effect of adjuvant RT was not analyzed in a multivariate regression analysis.…”

Understanding Lymphatic Drainage Pathways of the Ovaries to Predict Sites for Sentinel Nodes in Ovarian Cancer

“…25 Fetal tissues allow accurate exploration of the 3-dimensional (3D) anatomy of the human pelvic lymphatic system. The fetus of 20 weeks had a trisomy 14 with terminal 5p depletion.…”

“…By the end of the embryonic period (11th week), the formation of new plexuses has stopped, and major definitive lymphatic pathways can be identified. 25 The objective of this study was to analyze immunohistochemically and to reconstruct 3-dimensionally the lymphatic drainage pathways of the ovaries in human fetal pelves. Implications of these findings for the surgical management of epithelial ovarian cancer, including detection of sentinel nodes, will also be discussed.…”

Vaginal delivery of carboplatin-loaded thermosensitive hydrogel to prevent local cervical cancer recurrence in mice

“…Both cervix uteri and upper part of vagina is the most common site of tumor recurrence (Kraima et al, 2014). Although the vaginal drug delivery system (VDDS), includes tablets, tampons, films, sponges, foams, creams, gels, solutions, ointments, ovules, soft gelatin capsules, pessaries, douches, suppositories and vaginal rings, has long been used for the treatment of usual gynecological diseases (Yoo et al, 2006;Khutoryanskiy, 2011;Pereira & Bruschi, 2012;TugcuDemiroz et al, 2013).…”