Lymphangiomatosis of Bone

Solitary cystic lymphangioma

“…Less than 30 cases of bone lymphangiomas have been reported in the literature, and most of them are disseminated throughout the skeleton and/or associated with widespread organ and tissue involvement [2][3][4][5][6][7][8][9][10]. Solitary and localized cystic lymphangioma is exceptional [1,8,[11][12][13], and to our knowledge, its MR appearance has not been previously described in the English literature.…”

“…The most frequent sites of involvement are the tibia, humerus, ilium, skull, mandible, and vertebra [7,8].…”

Cystic angiomatosis of bone with sclerotic changes mimicking osteoblastic metastases

“…Although the term "(diffuse) cystic angiomatosis" has been generally used [15,20,[23][24][25][26][27][28][29], a wide variety of diagnostic terms such as "(diffuse) skeletal angiomatosis" [16,[30][31][32], "(diffuse) skeletal hemangiomatosis" [2][3][4][5][6], "lymphangiomatosis" [11][12][13], "cystic lymphangiectasia" [9,10], "multiple lymphangiectases" [7], and "hamartous hemolymphangiomatosis" [14,15] have been applied to what is probably the same condition. A few cases of multiple primary hemagiomas of bone have been reported and they have been considered a separate entity from cystic angiomatosis [17,33,34].…”

Percutaneous osteoplasty in treatment of bone lymphangiomatosis

“…Lymphangioma or bone lymphangiomatosis is a rare disease, with equal gender distribution and no hereditary tendency, that usually onsets during the first 20 years of life 3. It is most frequently localized in the diaphysis or metaphysis of the tibia and humerus as well as the iliac bone, skull, jaw and vertebrae.…”

“…Radiographic study revealed well defined lytic bone images of geographic features in the bones. Radiographic differential diagnosis includes neoplastic and proliferative bone marrow disorders, especially histiocytosis; as well as benign lesions such as solitary bone cysts, fibrous dysplasia, fibrous bone defects, cystic fibrous osteitis resulting from hyperparathyroidism and congenital generalized fibromatosis 35…”