Lymphangiomas in children: percutaneous sclerotherapy with an alcoholic solution of zein.

Dubois, Josée; Garel, Laurent; Abela, Anthony; Laberge, Louise Caouette; Yazbeck, Salam

doi:10.1148/radiology.204.3.9280239

Cited by 134 publications

(79 citation statements)

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“…Sclerotherapy has been tried for surgically unresectable lymphangiomas by using intralesional Bleomycin, OK 432 or a percutaneous injection of ethibloc, with successful outcomes [3,7]. Recurrences are known to occur in one-third of cases, regardless of the site of lesion and type of the adjunctive therapy which is given.…”

Section: Resultsmentioning

confidence: 99%

Lymphangioma Involving the Foetal Lower Limb, A Rare Condition Diagnosed on Prenatal Ultrasound

Hoblidar

et al. 2014

JCDR

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A 22-year-old primigravida came for a routine antenatal check up at 27 weeks of gestation. There was no history of a consanguineous marriage. There was no family history of any hereditary disease or delivery of a malformed foetus in the family. On examination, the fundal height corresponded to that seen at 30 weeks of gestation. Her obstetrics ultrasonography revealed the presence of a single live foetus with large, multicystic, multiseptate, variable sized anechoic areas in an echogenic background, which were found to involve one entire lower limb, which extended upto the ipsilateral pelvic region and were partly seen on the abdomen, on the ipsilateral side [Table/ Fig-1,2]. Colour Doppler showed no blood flow within the lesion. The other extremity appeared to be normal. No other structural anomalies were noted. Liquor was excessive. Parameters corresponded to those seen at 27 weeks of gestation. Patient went in to preterm labour at 30 weeks of gestation and delivered a baby with ambiguous genitalia. Baby showed massive oedema with congestion of right side of abdominal wall, back and whole of right lower limb, with involvement upto the toes. No other gross external malformations were noted. On autopsy, multiple sections taken from skin, which were studied, showed a cavernous lymphangioma which involved the right side of abdomen, back and right lower limb. Abdominal organs and the bones of the affected limb were normal. The foetal karyotype showed 46 XX chromosomes.

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Section: Resultsmentioning

confidence: 99%

Lymphangioma Involving the Foetal Lower Limb, A Rare Condition Diagnosed on Prenatal Ultrasound

Hoblidar

et al. 2014

JCDR

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“…Many different drugs were used to mimic what may occur spontaneously. The drugs included alcoholic solution of zein (Ethibloc) 10 , acetic acid", fibrin sealant', triamcinolone 13 In 1977 bleomycin, was proposed as a new sclerosing agent for cystic hygroma. 14°' S After that several trials have been reported using bleomycin with good or excellent results in up to 88% of cases.…”

Section: Discussionmentioning

confidence: 99%

Non surgical management of cystic lymphangioma

Rawat

Sinha

Kanojia

et al. 2006

Indian J Otolaryngol Head Neck Surg

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“…Many adjunctive therapies for treatment of lymphangioma have been described with varying results. Successful outcomes have been reported following the use of intralesional Bleomycin, sclerotherapy with OK432 or percutaneous embolization with Ethibloc [15][16][17] . Local injection of fibrin glue and laser photocoagulation have been used for postnatal treatment 18,19 .…”

Section: Discussionmentioning

confidence: 99%

Prenatal diagnosis of fetal abdominal lymphangioma by ultrasonography

Deshpande

Twining

O'Neill

2001

Ultrasound in Obstet & Gyne

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Lymphangiomas in children: percutaneous sclerotherapy with an alcoholic solution of zein.

Abstract: Percutaneous sclerotherapy with Ethibloc was a safe and effective procedure in the treatment of macrocystic and mixed lymphangiomas.

Cited by 134 publications

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Lymphangioma Involving the Foetal Lower Limb, A Rare Condition Diagnosed on Prenatal Ultrasound

Lymphangioma Involving the Foetal Lower Limb, A Rare Condition Diagnosed on Prenatal Ultrasound

Non surgical management of cystic lymphangioma

Prenatal diagnosis of fetal abdominal lymphangioma by ultrasonography

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