Lymphangioma Presenting as Hemoptysis in Pregnancy

Retroperitoneal lymphangioma in a pregnant patient: A case report and literature review

“…The search identified 15 articles concerning pregnant women with lymphangiomas [ [1] , [2] , [3] , [4] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] ]. Five articles were excluded from the analysis: four due to postpartum diagnosis [ 3 , [6] , [7] , [8] ] and one due to pregestational diagnosis [ 9 ].…”

“…Lymphangiomas diagnosed during pregnancy were documented in both abdominal [ 2 , 4 , 10 , 14 , 15 , 16 ] and extra-abdominal [ 1 , [11] , [12] , [13] ] locations, most commonly in the gastrointestinal tract ( Table 2 ). Notably, none of the reported gestational lymphangiomas were located retroperitoneally.…”

“…Notably, none of the reported gestational lymphangiomas were located retroperitoneally. Diagnosis occurred in the second trimester in five cases [ 1 , 10 , 11 , 13 , 16 ], in the third trimester in three cases [ 4 , 12 , 14 ], and in the first trimester in only two cases [ 2 , 15 ]. De novo diagnosis of lymphangioma during pregnancy could be attributed to symptoms associated with larger lymphangiomas during gestation [ 10 , 12 , 13 ].…”

“…Lymphangioma is a congenital benign tumor characterized by the benign focal proliferation of histologically well-differentiated lymphatic tissue, primarily consisting of dilated lymphatic channels lined by endothelium rich in connective tissue and smooth muscle cells, lymphocytes, fibroblasts, and collagen bundles [ 1 , 2 ]. There are three main subtypes, capillary, cavernous, and cystic, although they may all coexist within a single tumor [ 3 ].…”

“…Intra-abdominal lymphangiomas are less common [ 2 ]. The diagnostic approach typically involves imaging studies such as ultrasound or computed tomography, with diagnosis confirmed by histopathology following surgical resection, which is considered the definitive treatment for this condition [ 1 ].…”