Lymphadenitis cervicalis due to Mycobacterium interjectum in immunocompetent children

Rose, M. J.; Kitz, Richard J.; Mischke, A.; Enzensberger, R.; Schneider, Viktor; Zielen, Stefan

doi:10.1080/08035250410023025

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2024

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“…nov. ( 4 ). M. interjectum is an opportunistic pathogen mainly isolated from diseased lymph nodes ( 1 , 5 – 8 ) and the respiratory tract ( 5 , 9 – 11 ). A few other cases have caused meningoencephalitis ( 12 ) and cutaneous infection ( 13 ).…”

Section: Genome Announcementmentioning

confidence: 99%

Draft Genome Sequence of Mycobacterium interjectum Strain ATCC 51457 ^T

et al. 2016

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Section: Genome Announcementmentioning

confidence: 99%

Draft Genome Sequence of Mycobacterium interjectum Strain ATCC 51457 ^T

et al. 2016

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Mycobacterium interjectum causing submandibular lymphadenitis in a child

Lin,

Trieu

2024

Access Microbiology

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Nontuberculous mycobacteria (NTM) commonly manifest as cervical lymphadenitis in immunocompetent children. Only a few species, such as Mycobacterium avium complex (MAC), cause infection in children. With recent advances in gene sequencing, Mycobacterium interjectum has been identified as a rare cause of adenitis in children, with at least ten cases reported since 1993. Curative treatment for NTM lymphadenitis, particularly when caused by MAC, usually involves complete surgical excision of the affected lymph nodes. This case report highlights successful treatment of submandibular lymphadenitis caused by M. interjectum in a paediatric patient, despite multi-drug resistance in vitro.

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Mycobacterium interjectumLung Infection

Mirant-Borde

Álvarez

Johnson

2013

Case Reports in Pulmonology

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A 62-year-old male presented with productive cough, weight loss, and night sweats. CXR revealed a right upper lobe cavitary lesion. Evaluation was negative for Mycobacterium tuberculosis, and sputum revealed Mycobacterium avium intracellulare (MAI). Since his clinical course was atypical for MAI, further investigations were pursued which identified Mycobacterium interjectum in lung specimens, a very rarely described etiology of pulmonary disease. Appropriate therapy with rifampin, intravenous amikacin, trimethoprim/sulfamethoxazole (TMP/SMX), and ethambutol resulted in clinical and radiographic improvement. This is the third case described over a period of 20 years of destructive lung disease in an immunocompetent adult due to M. interjectum.

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Lymphadenitis cervicalis due to Mycobacterium interjectum in immunocompetent children

Abstract: The attention of clinicians needs to be drawn to an emerging mycobacterial pathogen which might be overlooked or misidentified in routine laboratory testing.

Cited by 4 publications

References 3 publications

Draft Genome Sequence of Mycobacterium interjectum Strain ATCC 51457 ^T

Draft Genome Sequence of Mycobacterium interjectum Strain ATCC 51457 ^T

Mycobacterium interjectum causing submandibular lymphadenitis in a child

Mycobacterium interjectumLung Infection

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Lymphadenitis cervicalis due to Mycobacterium interjectum in immunocompetent children

Abstract: The attention of clinicians needs to be drawn to an emerging mycobacterial pathogen which might be overlooked or misidentified in routine laboratory testing.

Cited by 4 publications

References 3 publications

Draft Genome Sequence of Mycobacterium interjectum Strain ATCC 51457 T

Draft Genome Sequence of Mycobacterium interjectum Strain ATCC 51457 T

Mycobacterium interjectum causing submandibular lymphadenitis in a child

Mycobacterium interjectumLung Infection

Contact Info

Product

Resources

About

Draft Genome Sequence of Mycobacterium interjectum Strain ATCC 51457 ^T

Draft Genome Sequence of Mycobacterium interjectum Strain ATCC 51457 ^T