Lymphadenectomy in Pelvic Exenteration for Recurrent Cervix Cancer

Barber, Hugh R. K.

doi:10.1001/jama.1971.03180250037008

“…Local recurrence of cervical cancer is estimated to be the principal cause of death in 59% of patients ( 2,18–20 ) . Results of surgical resection are well known for more than 20 years ( 21,22 ) and most authors consider that treatment of pelvic recurrence of cervical cancer should only be curative ( 10–13,21,23–25 ) . The aim of this work was to report on a single institutional experience of surgical treatment of resectable local recurrence in 70 consecutive patients.…”

Section: Discussionmentioning

confidence: 99%

Surgical resection of locally recurrent cervical cancer: a single institutional 70 patient series

Moutardier

¹

,

Houvenaeghel

²

,

Martino

³

et al. 2004

Int J Gynecol Cancer

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Pelvic recurrence of cervical cancer is a life-threatening situation and only local control can provide hope for remission. The aim of this study was to evaluate the role of surgery in the treatment of cervical cancer recurrence. This retrospective study analyzed a series of 70 patients who underwent resection of cervix locoregional recurrence. Thirteen patients had palliative salvage surgery for pelvic complications. Twenty-nine resections were considered as curative. Fifty recurrences required pelvic exenterations. The hospital mortality rate was 9% and the morbidity rate was 44%. Overall 5-year actuarial survival rate was 23%. Survival was significantly higher: (a) after curative resection and (b) after centropelvic recurrence resection. Local control was obtained in 48% of the cases and 13 patients are alive with a median follow-up of 75 months. In conclusion, the results of this small and heterogen series seem to justify an attempt to resection for centropelvic recurrences whenever possible. Palliative surgery should be reserved to salvage therapy and highly selected patients.

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“…Results of surgical resection are well known for more than 20 years (21,22) and most authors consider that treatment of pelvic recurrence of cervical cancer should only be curative (10)(11)(12)(13)21,(23)(24)(25) . The aim of this work was to report on a single institutional experience of surgical treatment of resectable local recurrence in 70 consecutive patients.…”

Section: Discussionmentioning

confidence: 99%

Surgical resection of locally recurrent cervical cancer: a single institutional 70 patient series

Moutardier¹,

Houvenaeghel²,

Martino³

et al. 2004

Int J Gynecol Cancer

View full text Add to dashboard Cite

Pelvic recurrence of cervical cancer is a life-threatening situation and only local control can provide hope for remission. The aim of this study was to evaluate the role of surgery in the treatment of cervical cancer recurrence. This retrospective study analyzed a series of 70 patients who underwent resection of cervix locoregional recurrence. Thirteen patients had palliative salvage surgery for pelvic complications. Twenty-nine resections were considered as curative. Fifty recurrences required pelvic exenterations. The hospital mortality rate was 9% and the morbidity rate was 44%. Overall 5-year actuarial survival rate was 23%. Survival was significantly higher: (a) after curative resection and (b) after centropelvic recurrence resection. Local control was obtained in 48% of the cases and 13 patients are alive with a median follow-up of 75 months. In conclusion, the results of this small and heterogen series seem to justify an attempt to resection for centropelvic recurrences whenever possible. Palliative surgery should be reserved to salvage therapy and highly selected patients.

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“…The best-quality RCT found compared cisplatin with no cisplatin with both groups receiving radiotherapy, 127 which gave an overall 5-year survival with cisplatin of 63% and without cisplatin of 59%. Only case series were found on radiotherapy (nine studies [84][85][86][87][88][89][90][91][92] ), chemoradiotherapy (seven studies [93][94][95][96][97][98][99] ), radical hysterectomy (seven studies [100][101][102][103][104][105][106] ) and pelvic exenteration (20 studies [107][108][109][110][111][112][113][114][115][116][117][118][119][120][121][122][123][124][125][126] ). The survival rates varied considerably, depending on the date of publication, characteristics of patients and type of treatment given.…”

Section: Effectiveness Reviewmentioning

confidence: 99%

Positron emission tomography/computerised tomography imaging in detecting and managing recurrent cervical cancer: systematic review of evidence, elicitation of subjective probabilities and economic modelling

Meads

¹

,

Auguste²,

Davenport³

et al. 2013

Health Technol Assess

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Reports are published in Health Technology Assessment (HTA) if (1) they have resulted from work for the HTA programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors.Reviews in Health Technology Assessment are termed 'systematic' when the account of the search appraisal and synthesis methods (to minimise biases and random errors) would, in theory, permit the replication of the review by others.

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Lymphadenectomy in Pelvic Exenteration for Recurrent Cervix Cancer

Cited by 26 publications

References 7 publications

Surgical resection of locally recurrent cervical cancer: a single institutional 70 patient series

Surgical resection of locally recurrent cervical cancer: a single institutional 70 patient series

Surgical resection of locally recurrent cervical cancer: a single institutional 70 patient series

Positron emission tomography/computerised tomography imaging in detecting and managing recurrent cervical cancer: systematic review of evidence, elicitation of subjective probabilities and economic modelling

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