Lymph Nodes

Wieczorek, Tad J.; Wakely, Paul E.

doi:10.1016/b978-1-4557-4462-6.00012-x

Cited by 3 publications

(2 citation statements)

References 134 publications

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“…Supernatant is discarded and the sediment is placed on filter paper and processed as a routine histopathology specimen. Cell blocks are useful in better preservation of the morphology, architecture, and further help in performing IHC to find the primary [8,9].…”

Section: Ancillary Techniquesmentioning

confidence: 99%

See 1 more Smart Citation

Lymph Node Cytology: Morphology and Beyond

Singh,

Balhara,

Rana

et al. 2023

Advances in Fine Needle Aspiration Cytopathology

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Fine needle aspiration cytology (FNAC), being minimally invasive, rapid, cost-effective provides a valuable first-line diagnostic tool in the evaluation of lymphadenopathies both benign and malignant. Various ancillary techniques namely immunocytochemistry, flow cytometry, cell blocks, and molecular studies further improve the diagnostic accuracy of FNACs. Targeted FNAC under ultrasound guidance optimizes cellular yield in palpable and non-palpable lymphadenopathies. FNAC proves to be indispensable at establishing tissue diagnosis in cases when surgical excision is unfeasible, as in elderly patients with comorbidities or in metastatic settings. Nevertheless, lymph node FNAC represents a daunting task owing to the multitude of benign and malignant causes of lymphadenopathy. To aid categorization and better communication to the clinician, an emphasis on classification and reporting of lymph node cytopathology using Sydney system is laid upon.

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Section: Ancillary Techniquesmentioning

confidence: 99%

“…FCM has a rapid turnaround time as compared to ICC, however, the morphology and staining characteristics are more preserved in ICC on cell blocks. Also, large cells, such as Reed-Sternberg (RS) cells, are better appreciated by ICC/IHC on cell blocks [9].…”

Section: Ancillary Techniquesmentioning

confidence: 99%