Lymph node ratio, number of excised nodes and sentinel-node concepts in breast cancer

Abstract

To cite this version:Nadia Peparini, Piero Chirletti. Lymph node ratio, number of excised nodes and sentinel-node concepts in breast cancer.

N0/N1, PNL, or LNR? The Effect of Lymph Node Number on Accurate Survival Prediction in Pancreatic Ductal Adenocarcinoma

“…10–13 LNR is the ratio between the numbers of positive and examined lymph nodes (ELN). Node ratio has been suggested as a tool to predict outcome in cancers of the esophagus, 14 stomach, 15 ampulla of Vater, 16,17 colon, 18 and even non-GI cancers such as breast 19 and melanoma. 20 However, some authors have suggested that absolute numbers of PLN are an independent 21–22 and better predictor 23 of survival than LNR.…”

The prognostic significance of early stage lymph node positivity in operable invasive breast carcinoma: number or stage

“…Assessment of LN status is fairly simple, inexpensive and characterised by a high degree of reproducibility and objectivity. In addition, most centres in the UK and elsewhere have adopted axillary node sampling, which provides assessment of a limited number of nodes (usually two to five nodes per case including the sentinel node) and subsequently thorough assessment of LN status and detection of early stage positivity 25 31. In clinical practice, LN, which are examined in all invasive breast carcinomas, are grouped into distinct categories (stages) that can stratify patients into prognostically distinct groups for the management purpose.…”