Lymph Node Metastasis From Carcinoma in Situ of the Penis: A Case Report

Eng, Tony Y.; Petersen, John P.; Stack, Richard S.; Judson, Patrick H.

doi:10.1097/00005392-199502000-00046

Cited by 14 publications

(6 citation statements)

References 16 publications

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“…Therefore, a rare case of metastasis of carcinoma in situ cannot be ruled out. Metastasis without an invasive component is extremely rare, with only three other documented cases in the medical literature ( 43 – 45 ). Kim et al ( 43 ) reported a case of inguinal and pelvic lymph node metastases from carcinoma in situ in the penis.…”

Section: Discussionmentioning

confidence: 99%

Occult urothelial carcinoma with mediastinal metastasis: A case report

Zheng,

Peng,

et al. 2024

Oncol Lett

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Occult urothelial carcinoma (UC), particularly with mediastinal metastases, is an uncommon clinical occurrence. The present study describes the unusual case of a 70-year-old male patient who developed mediastinal metastases from an occult UC. Histological evaluations and immunohistochemical features of the mediastinal tumor were indicative of UC; however, extensive imaging failed to identify the primary urological lesion. The findings suggest that mediastinal metastases from UCs, despite their rarity, should be considered in cases where patients with mediastinal tumors exhibit chest-related symptoms. Prompt pathological examinations are crucial for ascertaining the nature and origin of the tumor. Moreover, individualized treatment should be performed in strict accordance with the established oncology guidelines.

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Section: Discussionmentioning

confidence: 99%

Occult urothelial carcinoma with mediastinal metastasis: A case report

Zheng,

Peng,

et al. 2024

Oncol Lett

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“…6 Metastasis from penile carcinoma in situ is extremely rare, as there have only been 2 other reported cases. 7,8 Avrach and Christensen described an aggressive case of penile carcinoma in situ. 7 The patient underwent circumcision and inguinal lymph node dissections that later revealed cancerous tissue.…”

Section: Discussionmentioning

confidence: 99%

“…7 Eng and colleagues reported another case of a similar lesion with metastasis to the inguinal and para-aortic lymph nodes. 8 The patient was initially treated with circumcision and topical 5-fluorouracil until metastatic disease was discovered several years later, for which he underwent systemic chemotherapy and an inguinal lymph node dissection. 8 The detection of metastatic disease from carcinoma in situ is therefore often incidental or delayed.…”

Section: Discussionmentioning

confidence: 99%

A rare case of penile cancer in situ metastasizing to lymph nodes

Kim

Garcı́a

Touma

et al. 2013

CUAJ

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“…Although unusual, development of lymph node metastasis has been reported after treatment of PIN with circumcision combined with 5-FU (23). Progress of PfN to invasive penile cancer has been reported after CO^ laser ablation (24) and after PDT combined with topical 5-FU (25).…”

Section: Discussionmentioning

confidence: 99%

Penile Intraepithelial Neoplasia: Results of Photodynamic Therapy

Paoli¹,

Bratel²,

Löwhagen³

et al. 2006

Acta Derm Venereol

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Failure of response to treatment or recurrent disease is often noted in patients with penile intraepithelial neoplasia. Photodynamic therapy has recently been added to the list of treatment modalities used for this diagnosis. Our primary objective was to study the results of photodynamic therapy in the treatment of penile intraepithelial neoplasia in men over the age of 40 years. Ten patients aged 42-82 years with histopathologically confirmed lesions were studied. Lesions initially responded to photo-dynamic therapy in 7 out of 10 patients. Four of these patients presented no recurrences during a mean follow-up of 35 months, and were completely cleared after 2-8 treatments (mean 4.5 treatments). Three patients presented recurrences after treatment. No patient developed invasive penile cancer (mean follow-up 46.5 months). Photodynamic therapy is an alternative in the treatment of penile intraepithelial neoplasia, although prospective randomized trials are required to provide therapeutic guidelines.

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Lymph Node Metastasis From Carcinoma in Situ of the Penis: A Case Report

Cited by 14 publications

References 16 publications

Occult urothelial carcinoma with mediastinal metastasis: A case report

Occult urothelial carcinoma with mediastinal metastasis: A case report

A rare case of penile cancer in situ metastasizing to lymph nodes

Penile Intraepithelial Neoplasia: Results of Photodynamic Therapy

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