“…In order to evaluate the likelihood that a patient's high-degree heart block is caused by LC, we proposed the Suspicious Index in Lyme Carditis (SILC) score ( Table 1). [22] This novel risk score assigns weights to the following risk factors: age < 50; [5,6,19] male sex (compared to relatively equal prevalence of Lyme disease by sex, LC has a strong male predominance of approximately 3:1); [2] outdoor activity or endemic area; [2,23] characteristic symptoms of Lyme disease, including fever, malaise, arthralgia, dyspnea, pre-syncope, and syncope; [4,24] history of a tick bite; [19] and erythema migrans. [6] In a preliminary validation study, the SILC risk stratification tool had a sensitivity of 93.2%.…”