Lyme Carditis

Scheffold, N; Herkommer, Bernhard; Kandolf, Reinhard; May, Andreas E.

doi:10.3238/arztebl.2015.0202

Cited by 53 publications

(64 citation statements)

References 46 publications

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“…The involvement of the heart is observed in 4-10% of patients with LB, of whom 90% have Lyme carditis (90,91 If heart involvement in LB is suspected, a cardiological examination is suggested. The following investigations should be addressed: 12-channel ECG and 24-h ECG Holter (query: rhythm analysis, PQ interval, QRS width, ectopic beats), chest X-ray (question: heart size, congestion); echocardiography (diameter, ejection fraction, abnormal wall movement, pericardial effusion); cardiac MRI, and in selected cases myocardial biopsy for histological examination and cultural isolation of Borrelia (96).…”

Section: Heart Symptomsmentioning

confidence: 99%

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A Practical Approach to the Diagnosis of Lyme Borreliosis: From Clinical Heterogeneity to Laboratory Methods

2020

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Clinical evaluation of Lyme Borreliosis (LB) is the starting point for its diagnosis. The patient's medical history and clinical symptoms are fundamental for disease recognition. The heterogeneity in clinical manifestations of LB can be related to different causes, including the different strains of Borrelia, possible co-infection with other tick transmitted pathogens, and its interactions with the human host. This review aims at describing the heterogeneous symptoms of Lyme Borreliosis, as well as offering a practical approach for recognition of the disease, both in terms of clinical features and diagnostic/research tools.

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Section: Heart Symptomsmentioning

confidence: 99%

“…The involvement of the heart is observed in 4–10% of patients with LB, of whom 90% have Lyme carditis ( 90 , 91 ). The most frequent manifestations are:…”

Section: General and Extracutaneous Clinical Manifestationsmentioning

confidence: 99%

A Practical Approach to the Diagnosis of Lyme Borreliosis: From Clinical Heterogeneity to Laboratory Methods

2020

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“…Впоследствии в тканях миокарда образуются трансмуральные воспали-тельные очаги с лентовидной эндокардиальной лимфоцитарной инфильтрацией. Спирохеты мо-гут быть определены рядом или в пределах этих инфильтратов, между мышечными волокнами или внутри эндокарда [28].…”

Section: окончание таблицыunclassified

Сlinical Presentation and Concentration of Cytokines Serum of Patients With Form Without Erythema of Lyme Disease

Бондаренко¹,

Sapozhnikova²

2017

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“…95% of reported cases come from 12 Northeastern and 2 North Midwestern states [1]. LC is a rarer manifestation of LD [2]. LC may present with or without other manifestations of LD and could involve all layers of the heart: myocardium [3–7], pericardium [8, 9], endocardium [10–13], or pancarditis [4, 14, 15].…”

Section: Introductionmentioning

confidence: 99%

First case report of inducible heart block in Lyme disease and an update of Lyme carditis

2019

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Background Lyme disease (LD), is the most common vector-borne illness in the US and Europe, with predominantly cutaneous, articular, cardiac and neuro-psychiatric manifestations. LD affects all layers of the heart and every part of the conducting system. Carditis is a less common manifestation of LD. Heart block (HB) as the initial and sole manifestation of LD is rare. Inducible HB has never been reported in LD. We report a case of heart block (HB) inducible with exercise and reversible with rest. Case presentation A 37-year-old male presented to the emergency department after experiencing two episodes of syncope while at work. He presented, with a heart rate of 57 bpm, and the ECG showed sinus bradycardia with first degree AV block. The PR interval was 480 ms (NL 120–200 ms). Physical exam was unremarkable. The cardiologist’s initial impression was vaso-vagal attack. He developed high degree AV block during a stress test for the initial work up, which resolved on cessation of exercise. A similar episode while walking in the hallway, resolved at rest. The high degree AV block appeared inducible with exercise and reversible with rest. His Lyme serology was strongly positive. He was treated with ceftriaxone and doxycycline. After completing treatment, the patient had a normal ECG and returned to work without limitations, doing manual labor. Conclusions Manifestations of Lyme carditis (LC) vary from asymptomatic and symptomatic electrocardiographic changes and heart block (HB) reversible with treatment, to sudden death. HB as the sole and initial presentation of LC is rare. There have been no reports of inducible HB in LD. Here we present a case of inducible and reversible high degree HB in a case of LC and an update of literature. Exercise and stress testing should be avoided in suspected cases of LC until resolution of carditis. Lyme carditis should be suspected in individuals with cardiac manifestations in an endemic area, particularly in the younger patients with no other etiology evident.

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Lyme Carditis

Abstract: SUMMARYBackground: There are 60 000 to 100 000 new cases of borreliosis in Germany each year. This infectious disease most commonly affects the skin, joints, and nervous system. Lyme carditis is a rare manifestation with potentially lethal complications.

Cited by 53 publications

References 46 publications

A Practical Approach to the Diagnosis of Lyme Borreliosis: From Clinical Heterogeneity to Laboratory Methods

A Practical Approach to the Diagnosis of Lyme Borreliosis: From Clinical Heterogeneity to Laboratory Methods

Сlinical Presentation and Concentration of Cytokines Serum of Patients With Form Without Erythema of Lyme Disease

First case report of inducible heart block in Lyme disease and an update of Lyme carditis

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