Abstract:head) to 1.11 (rectum) for the composite plan and from 1.00 to 1.27 for individual treatment beams. For the thorax, estimates of the tumor RBE ranged from 1.05 to 1.06; composite plan RBE estimates for OARs (heart, lungs, spinal cord, esophagus, breast, brachial plexus) ranged from 1.02 (breast) to 1.2 (spinal cord). Biological hot spots (RBE up to 1.27) were noted to arise near the distal edge of the Bragg peak. Conclusion: Patient-and tumor-specific RBE estimates from a model that accounts for spatial variat… Show more
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