Lycopene, an Antioxidant Carotenoid, Attenuates Testicular Injury Caused by Ischemia/Reperfusion in Rats

Effectiveness of Aqueous and Alcoholic Extracts of Barberry, Jujube, and Saffron Against Oxidative Stress in Streptozotocin-Induced Diabetic Rats

“…Previous studies found that carotenoids inhibit free radicals-mediated lipid peroxidation (25). It is possible that jujube fruit extract, with remarkable amounts of carotenoid, prevents the accumulation of hydrogen peroxide by increasing the activity of enzymes such as glutathione peroxidase (26).…”

Preventive Effects of Cyclosporine A Combined With Prednisolone and Melatonin on Contralateral Testicular Damage After Ipsilateral Torsion-Detorsion in Pubertal and Adult Rats

“…[22][23][24] Many groups have proposed that I/R injury is the main cause of contralateral damage after TT. 6,25,26 However, there are sparse published data on the effects of antioxidants on contralateral testicular damage after TT. Melatonin, as used in this study, is a direct scavenger of toxic hydroxyl radicals and also stimulates activity of the antioxidative enzyme glutathione peroxidase.…”

Effect of lycopene on oxidative stress induced duringd-galactosamine/lipopolysaccharide-sensitized liver injury in rats

“…Numerous studies have indicated the health benefits of consuming lycopene and demonstrated its preventive role in a number of chronic diseases including various types of cancers (Agarwal & Rao, 2000;Bhuvaneswari & Nagini, 2005;Cohen, 2002;Giovannucci, 2002;Khachik et al, 2002). This carotenoid phytonutrient is found to be the most effective antioxidant among all tested carotenes and xanthophylls (Atessahin et al, 2007;Di Mascio et al, 1989;Hekimoglu et al, 2009;Kong et al, 2010). It offers important health benefits, particularly, in regard to prostate, lung, heart, liver and skin health.…”