“…The major etiopathogenetic causes of otosclerosis are considered to be genetic factors, collagen defects, collagen autoimmunity and viral infection (Chole and McKenna, 2001). So far, numerous histopathological studies on the SVJ have been performed (Davies, 1948;Harty, 1953;Brunner, 1954;Wolff and Bellucci, 1956;Gussen, 1968Gussen, , 1969Bolz and Lim, 1972;De Souza et al, 1991;Okumura and Iwai-Liao, 1993;Merchant et al, 2001;Whyte et al, 2002). In the normal SVJ, both the vestibular surface and the rim of the stapedial base are covered with hyaline cartilage.…”