Luvigenin and hecogenin from the leaves of Yucca gloriosa

Pkheidze, T. A.; Gvazava, L. N.; Кемертелидзе, Э. П.

doi:10.1007/bf00630337

Cited by 2 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…illustrates a 3D graph showcasing the predicted and calculated activity of estrone (4) as an ovulation inhibitor. Luvigenin ( 21), a steroid, has been detected in the leaves of Metanarthecium luteoviride [52], Yucca gloriosa [53], and Allium giganteum [54]. Additionally, a cancer-fighting steroid called cayaponoside A4 (22) was isolated from the roots and bark of the Tayuya tree, which can be found in the Amazon rainforest across Bolivia, Brazil, and Peru [55][56][57].…”

Section: Steroids Bearing Aromatic Ring a In Plantsmentioning

confidence: 99%

“…Luvigenin ( 21), a steroid, has been detected in the leaves of Metanartheciu [52], Yucca gloriosa [53], and Allium giganteum [54]. Additionally, a cancer-figh called cayaponoside A4 (22) was isolated from the roots and bark of the Tayuya can be found in the Amazon rainforest across Bolivia, Brazil, and Peru [55-57 23), was isolated from th medicinal plant Maytenus chuchuhuasca [58].…”

Section: Steroids Bearing Aromatic Ring a In Plantsmentioning

confidence: 99%

See 1 more Smart Citation

Biological Activity and Structural Diversity of Steroids Containing Aromatic Rings, Phosphate Groups, or Halogen Atoms

Dembitsky

2023

Molecules

View full text Add to dashboard Cite

This review delves into the investigation of the biological activity and structural diversity of steroids and related isoprenoid lipids. The study encompasses various natural compounds, such as steroids with aromatic ring(s), steroid phosphate esters derived from marine invertebrates, and steroids incorporating halogen atoms (I, Br, or Cl). These compounds are either produced by fungi or fungal endophytes or found in extracts of plants, algae, or marine invertebrates. To assess the biological activity of these natural compounds, an extensive examination of referenced literature sources was conducted. The evaluation encompassed in vivo and in vitro studies, as well as the utilization of the QSAR method. Numerous compounds exhibited notable properties such as strong anti-inflammatory, anti-neoplastic, anti-proliferative, anti-hypercholesterolemic, anti-Parkinsonian, diuretic, anti-eczematic, anti-psoriatic, and various other activities. Throughout the review, 3D graphs illustrating the activity of individual steroids are presented alongside images of selected terrestrial or marine organisms. Additionally, the review provides explanations for specific types of biological activity associated with these compounds. The data presented in this review hold scientific interest for academic science as well as practical implications in the fields of pharmacology and practical medicine. The analysis of the biological activity and structural diversity of steroids and related isoprenoid lipids provides valuable insights that can contribute to advancements in both theoretical understanding and applied research.

show abstract

Section: Steroids Bearing Aromatic Ring a In Plantsmentioning

confidence: 99%

Section: Steroids Bearing Aromatic Ring a In Plantsmentioning

confidence: 99%

Biological Activity and Structural Diversity of Steroids Containing Aromatic Rings, Phosphate Groups, or Halogen Atoms

Dembitsky

2023

Molecules

View full text Add to dashboard Cite

show abstract

Naturally occurring aromatic steroids and their biological activities

Dembitsky

Savidov

Poroikov

et al. 2018

Appl Microbiol Biotechnol

View full text Add to dashboard Cite

The present review describes the distribution and biological activities of natural mono-, di-, and triaromatic steroids. It is shown that the producers of aromatic steroids are microorganisms, fungi, and marine invertebrates, and also they were found in plants, animals, marine sediments, and karst deposits. Eighty biologically active aromatic steroids likely have an anti-tumor, anti-inflammatory, and neuroprotection activity with a confidence of 78 to 92%. The structures and predicted biological activities of aromatic steroids are available. This review emphasizes the role of aromatic steroids as an important source and potential leads for drug discovery and they are of great interest to chemists, physicians, biologists, pharmacologists, and the pharmaceutical industry.

show abstract

Luvigenin and hecogenin from the leaves of Yucca gloriosa

Cited by 2 publications

References 3 publications

Biological Activity and Structural Diversity of Steroids Containing Aromatic Rings, Phosphate Groups, or Halogen Atoms

Biological Activity and Structural Diversity of Steroids Containing Aromatic Rings, Phosphate Groups, or Halogen Atoms

Naturally occurring aromatic steroids and their biological activities

Contact Info

Product

Resources

About