Luteinizing hormone releasing hormone agonist for postpartum contraception

Abstract

GnRH agonists have advantages over steroids for hormonal contraception during the postpartum period in breastfeeding women. Symptoms of hypoestrogenism were not reported any time in either the controls or the treated groups, as estrone levels were not suppressed to menopausal values. Once-daily administration of GnRH agonist could be a reliable, acceptable and safe contraceptive method during the postpartum period in breastfeeding women. More information is required to establish GnRH analog contraceptive efficacy.

GnRH agonist for postpartum contraception: Biochemical, hormonal and endometrial effects

“…In recent years several potent GnRH analogs have become available for female contraception, and one of them, buserelin, has been studied in lactating women and has shown good results [5,6]. However, the metabolic effects of treatment have not been investigated in these trials.…”