Luteinized Ovarian Thecoma in a Postmenopausal Women Presenting with Virilization

Abstract

We report a case of luteinizing thecoma in a 58-year-old postmenopausal woman who presented with progressive androgenic features and hypertension of one year duration. She did not notice a significant change in her body weight or appetite. Her total serum testosterone level was 4.5 ng/mL. Ultrasound scan revealed a normal-sized uterus and a right-sided solid ovarian mass of 5 cm × 5 cm. Left ovary was normal. She had a total abdominal hysterectomy, bilateral salpingo-oophorectomy, and an omentectomy performed. Histological examination confirmed the diagnosis of luteinized thecoma. This case illustrates the necessity to consider the rare possibility of luteinized ovarian thecoma as a cause for virilization in a menopausal woman.

Value of 3.0 T diffusion-weighted imaging in discriminating thecoma and fibrothecoma from other adnexal solid masses

“…According to the MRI findings in the present study, all the thecomas were solid-component masses, regardless of the lesion size, except for one cystic and solid mass, with a pathological diagnosis of luteinized thecoma, which is described in the literature as a rare condition [15]. In another study of 19 patient samples, the authors reported four lesions that presented as mostly cystic masses on cross-sectional imaging [3], which could represent cystic degeneration or stromal edema.…”

Androgenproduzierende Tumoren

“…Das sind seltene von den Thekazellen des Ovars ausgehende endokrin aktive Stromatumoren. Sie treten meist in der Peri-und Postmenopause auf [18]. Ein Anteil von 70% sezerniert Östro-gene, es gibt jedoch auch androgenproduzierende Thekome.…”