Lupus anticoagulant associated with extracranial internal carotid artery occlusion.

Alpert, Jack N.; White, Megan; Perusquia, E

doi:10.1161/str.21.12.1759a

Cited by 4 publications

(3 citation statements)

References 3 publications

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“…These angiographic findings suggest a link between the antiphospholipid antibody syndrome and cerebral arteriopathies and raise the possibility that arteriopathies and a hypercoagulable state are both implicated in the increased risk of arterial stroke. Whereas most arteriopathies in stroke patients with the antiphospholipid antibody syndrome involve the intracranial circulation, occasionally the extracranial internal carotid artery is affected [6]. Little is known about this manifestation and about the natural progression of stenosis of the extracranial internal carotid artery in patients with the antiphospholipid antibody syndrome.…”

Section: Introductionmentioning

confidence: 99%

Bilateral Internal Carotid Artery Occlusion Associated with the Antiphospholipid Antibody Syndrome

Anand

Mann²,

Fischbein

et al. 2014

Case Rep Neurol

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A 39-year-old woman presented with a right-hemispheric stroke 1 year after she had suffered a left-hemispheric stroke. Her diagnostic workup was notable for bilateral occlusions of the internal carotid arteries at their origins and a positive lupus anticoagulant antibody test. There was no evidence of carotid dissection or another identifiable cause for her carotid occlusions. These findings suggest that the antiphospholipid antibody syndrome may be implicated in the pathological changes that resulted in occlusions of the extracranial internal carotid arteries. Young stroke patients who present with unexplained internal carotid artery occlusions may benefit from testing for the presence of antiphospholipid antibodies.

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Section: Introductionmentioning

confidence: 99%

Bilateral Internal Carotid Artery Occlusion Associated with the Antiphospholipid Antibody Syndrome

Anand

Mann²,

Fischbein

et al. 2014

Case Rep Neurol

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“…The following positive antiphospholipid antibodies were detected: aCL in 14 patients (73.68%), LAC in 9 patients (47.3%), A-B2GLP in 6 patients (31.5%) and aPE in 1 patient (5.2%). The different vessels involved included the internal carotid artery, aorta and coronary arteries in four patients each (21.05%), the vertebral artery and cerebral arteries in three patients (15.7%), and the superficial femoral artery in one patient (5.2%) [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] .…”

Section: Discussionmentioning

confidence: 99%

Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review

Al-Banaa

Alshaikhli

AL-Hareeri

et al. 2021

European Journal of Case Reports in Internal Medicine

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Antiphospholipid syndrome (APS) is a multisystemic autoimmune disease which presents with thromboembolic disease, pregnancy complications and the presence of antiphospholipid antibodies. There are some reports of arterial dissections in different sites of the body associated with APS. We describe two patients with APS who developed ischaemic stroke as a result of vertebral artery dissection in the absence of acquired and genetic risk factors for arterial dissection. We also conducted a systematic review of the literature for cases of arterial dissection associated with APS. We suspect that APS may be a potential cause of vasculopathy and arterial dissection. Further research is needed to explore this possible association.

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“…Antiphospholipid syndrome presenting with unilateral parotid swelling due to external carotid artery thrombus was unique, and as we went through previous literature, involvements of internal carotid artery, even bilateral, were documented in association with APS. Alpert et al [3] showed occlusion of extracranial part of internal carotid artery. Marques et al [4] documented left internal carotid artery thrombus in a 48-year-old female who presented with stoke.…”

Section: Discussionmentioning

confidence: 99%

Parotid swelling due to external carotid artery thrombus—a rare manifestation in antiphospholipid syndrome

Basu

Hazra

Mondal

et al. 2019

Oxford Medical Case Reports

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Vascular complications in forms of venous and arterial thrombi are common scenario in antiphospholipid syndrome with raised titer of antibodies. Here we describe an 18 years old female who was admitted with right parotid swelling due to external carotid artery thrombi within gland parenchyma in antiphospholipid syndrome, with past history of right lower leg arterial occlusion and digital gangrene.

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Lupus anticoagulant associated with extracranial internal carotid artery occlusion.

Cited by 4 publications

References 3 publications

Bilateral Internal Carotid Artery Occlusion Associated with the Antiphospholipid Antibody Syndrome

Bilateral Internal Carotid Artery Occlusion Associated with the Antiphospholipid Antibody Syndrome

Arterial Dissection in Antiphospholipid Syndrome Patients: Two Case Reports and a Literature Review

Parotid swelling due to external carotid artery thrombus—a rare manifestation in antiphospholipid syndrome

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