Lungworm in cattle: treatment and control

Forbes, Andrew

doi:10.12968/live.2018.23.3.102

Cited by 4 publications

(4 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, the larvae that were recovered on day 15 post‐treatment were well within this period of activity. The expected speed of action of MLs against D. viviparus in order to eliminate adult worms from the lungs is estimated to be ∼24 hours, 15 so the presence of larvae indicates the presence of patent adults. With a pre‐patent period of 21‒28 days, the females producing these larvae must have been present at some early developmental stage during the time of treatment.…”

Section: Discussionmentioning

confidence: 99%

Inefficacy of ivermectin and moxidectin treatments against Dictyocaulus viviparus in dairy calves

Campbell,

Forbes,

McIntyre

et al. 2024

Veterinary Record

Self Cite

View full text Add to dashboard Cite

BackgroundThe bovine lungworm Dictyocaulus viviparus negatively impacts bovine health and leads to substantial economic losses. Lungworm infections can be difficult to manage due to the unpredictable and severe nature of clinical outbreaks. Despite the widespread use of macrocyclic lactones (MLs) in grazing cattle in the UK, there have been no confirmed reports of resistant lungworms to date, with only one case of anthelmintic‐resistant (ML) lungworm confirmed worldwide.MethodsLungworm Baermann filtrations were conducted on first‐season grazing dairy calves as part of a wider study investigating anthelmintic resistance in gastrointestinal nematodes in Scotland using the faecal egg count reduction test.ResultsClinical signs and significant numbers of lungworm larvae in faeces were observed after treatment with either ivermectin or moxidectin.LimitationsThere are no established guidelines for the diagnosis of resistant lungworms in the field. Currently, resistance can only be diagnosed after a controlled efficacy test has been conducted. This limits the conclusions that can be drawn; however, they are highly suggestive of resistance.ConclusionThis short report describes the inefficacy of ivermectin and moxidectin against D. viviparus and is highly suggestive of ML resistance.

show abstract

Section: Discussionmentioning

confidence: 99%

Inefficacy of ivermectin and moxidectin treatments against Dictyocaulus viviparus in dairy calves

Campbell,

Forbes,

McIntyre

et al. 2024

Veterinary Record

Self Cite

View full text Add to dashboard Cite

show abstract

“…The modern-broad spectrum benzimidazole, imidazothiazole and macrocyclic lactone anthelmintic drugs are effective against L 4 and adult stages of Dictyocaulus spp. in sheep and cattle [91]. In most countries, these drugs are not licensed for use in goats.…”

Section: Discussionmentioning

confidence: 99%

“…Drugs with efficacies less than 100%, can still be useful for lungworm control, but their use risks selection for anthelmintic resistance. Poor efficacy against certain parasite species may be due to inherent pharmacological properties of the drugs, which may be stage specific, for example differing between adults and migrating stages in the lymphatics [91].…”

Section: Discussionmentioning

confidence: 99%

The Prevalence and Control of Lungworms of Pastoral Ruminants in Iran

et al. 2022

View full text Add to dashboard Cite

Lungworms of the genera Dictyocaulus, Muellerius, Protostrongylus, and Cystocaulus are common helminths of domestic and wild ruminants with substantial veterinary and economic importance. Several studies have assessed the presence and prevalence of lungworm infections in ruminants in Iran. This report compiles the available scientific information about the occurrence of lungworms in domestic and wild ruminants in Iran between 1931 and June 2022 to give an insight into their epidemiology, and where possible to describe drug treatment efficacy. For this purpose, national and international scientific databases were searched. Overall, 54 publications comprising 33 articles in peer-reviewed journals, 8 conference papers, and 13 dissertations were evaluated regarding prevalence data; and an additional 4 peer-reviewed articles were evaluated regarding drug efficacy. Seven species of lungworms, namely Dictyocaulus filaria, Dictyocaulus viviparus, Dictyocaulus eckerti, Protostrongylus rufescens, Protostrongylus raillietti, Muellerius capillaris, and Cystocaulus ocreatus have been recorded from different ruminant hosts in Iran. Thirty-three studies conducted on small ruminant (sheep and goat) lungworms reported prevalences of lungworm infection of 11.6%, 45.81% and 66.29% using abattoir meat inspection, Baermann technique and fecal flotation, respectively. Eight studies conducted on large ruminants (cattle and water buffalo) reported prevalences of infection of 14.83%, 13.98% and 5% using abattoir meat inspection, the Baermann technique and fecal flotation, respectively. The prevalence of infection in wild ruminants was variable across examined species; 38% in urial, 37% in wild goats, 5% in goitered gazelles and 67% in red deer, in addition to a single case report in roe deer. There are few contemporary studies assessing the efficacy of currently available broad-spectrum anthelmintic compounds against lungworms in Iran. The high prevalence of multiple lungworm species in Iran, combined with a lack of information about drug efficacy, supports the need to improve the understanding of these important nematode parasites and inform the development of sustainable control strategies. The aim of this review and meta-analysis is to provide a baseline for future conventional parasitology and next generation molecular epidemiological studies of lungworm infection in pastoral ruminants in Iran.

show abstract

“…A literature search was conducted for information regarding expected speed of action of eprinomectin. While the speed of action of macrocyclic lactones against D viviparus has not been specifically measured, it has been estimated at approximately 24 hours 4 . Another study conducted in 1994 5 showed the speed of action to be similar to that of the benzimidazoles at 36 hours 6…”

mentioning

confidence: 99%