Lungs

Treves, S. Ted; Packard, Alan B.

doi:10.1007/978-1-4757-4205-3_11

Cited by 4 publications

(1 citation statement)

References 96 publications

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“…Lung washout rates following inhalation of radon by children were not available during development of the proposed model. In lieu of this data, lung washout rates measured in children who briefly inhaled krypton (Ciofetta et al 1980) or xenon (Treves et al 1974, Treves and Packard 1995, Goo 2013) mixed with air were used to estimate age-specific removal half-time of radon. Consistency between observed half-times for lung washout of krypton (Ellis et al 1977) and xenon (Susskind et al 1977) and observations for radon (Harley et al 1994) in adults suggests that age-specific washout rates for krypton and xenon are reasonable estimates for radon.…”

Section: Methodsmentioning

confidence: 99%

An age- and sex-specific biokinetic model for radon ^*

Samuels,

Marsh,

Leggett

2023

J. Radiol. Prot.

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Publication 137 of the International Commission on Radiological Protection (ICRP) describes a biokinetic model for radon used to derive dose coefficients for occupational intake of radon isotopes. The model depicts transfer of inhaled or ingested radon to blood, exchange of radon between blood and tissues, and gradual loss of radon from the body based on physical laws governing transfer of a non-reactive and soluble gas between materials. This paper describes an age- and sex-specific variation of that model developed for use in an upcoming ICRP series of reports on environmental intake of radionuclides by members of the public titled ‘Dose Coefficients for Intakes of Radionuclides by Members of the Public’. The proposed model modifies the model structure and transfer coefficients presented in Publication 137 to allow more realistic dosimetric treatment of bone marrow and breast and expands the model to address pre-adult ages, based on the physical principles used in the development of the model of Publication 137 together with anatomical and physiological changes occurring during human development.

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