Lung Volumes in a Mouse Model of Pulmonary Allergic Inflammation
Andrés Rojas-Ruiz,
Magali Boucher,
Cyndi Henry
et al.
Abstract:Purpose
Air trapping, often attested in humans by elevated residual volume (RV) and ratio of RV on total lung capacity (RV/TLC), is frequently observed in asthma. Confirming these alterations in experimental asthma would be important for translational purposes. Herein, lung volumes were investigated in a mouse model of pulmonary allergic inflammation.
Methods
Eight- to 10-week-old male C57BL/6 and BALB/c mice were exposed once daily to intranasal house dus… Show more
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