Objective
Bâline imaging by lung ultrasound (LUS) is a new tool for evaluating subclinical pulmonary congestion. The aim of this study was to explore the prognostic value of Bâline number at admission in predicting symptomatic heart failure (HF) during hospitalization in acute anterior wall STEMI patients.
Methods
This was a prospective cohort study which consecutively enrolled 96 anterior wall STEMI patients without dyspnea at admission. Pulmonary auscultation, NTâproBNP test, LUS, and echocardiography were performed within 5Â hours after primary PCI. Rale occurrence, plasma NTâproBNP levels, Bâline number, LVEF, E/eâ were recorded, and their predictive value for HF inâhospital was analyzed.
Results
A total of 19 patients developed symptomatic HF. Median Bâline number, NTâproBNP levels, and E/eâ in the HF group were higher than those of the nonheartâfailure (NHF) group (PÂ <Â 0.001) while LVEF was lower (PÂ =Â 0.002). There was no statistical difference in rale occurrence between the two groups. Multivariate logistic regression demonstrated that Bâlines, E/eâ, and NTâproBNP independently predicted HF during hospitalization. According to the area under the ROC curve, the strongest predictor is Bâlines (0.972), followed by NTâproBNP (0.936) and E/eâ (0.928), and combining the three indicators was better than any single parameter (PÂ =Â 0.048). Bâline cutoff â„18 could well predict HF event with specificity and sensitivity of 94.7% and 94.8%, respectively.
Conclusion
Subclinical pulmonary congestion reflected by Bâlines can independently predict symptomatic HF during hospitalization in patients with anterior wall STEMI, LUS will act as a complementary tool for evaluating cardiac function.