Lung transplantation for lymphangioleiomyomatosis

Pechet, Taine T.; Singhal, A.K.; Meyers, Bryan F.; Guthrie, Tracey J.; Battafarano, Richard J.; Trulock, Elbert P.; Cooper, James D.; Patterson, G.A.

doi:10.1016/s1053-2498(00)00350-8

Cited by 19 publications

(31 citation statements)

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“…LAM compares favourably to patients transplanted for other indications [38,88,103,104]. In a recent survey the actuarial survival of lung transplantation for LAM was 86% at 1 yr, 76% at 3 yrs, and 65% at 5 yrs [104].…”

Section: Treatment and Follow-up Of Angiomyolipomamentioning

confidence: 99%

“…Conservative treatments are associated with higher rates of recurrence than pleurodesis via chest tube or appropriate surgical interventions [10,55]. Lung transplantation in patients with previous thoracic surgery or pleural procedures may be associated with increased technical difficulty and an increased risk or perioperative bleeding [38,55,87,88]. …”

Section: Management Of Pneumothoraxmentioning

confidence: 99%

“…Recurrent LAM has been identified at post mortem examination or in biopsies performed for other purposes. Recurrent LAM does not seem to affect survival post transplantation [38,88,104,[109][110][111].…”

Section: Which Type Of Transplantation Is Indicated In Lam?mentioning

confidence: 99%

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European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis

Johnson¹,

Cordier²,

Lazor³

et al. 2009

European Respiratory Journal

466

561

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Section: Treatment and Follow-up Of Angiomyolipomamentioning

confidence: 99%

Section: Management Of Pneumothoraxmentioning

confidence: 99%

See 1 more Smart Citation

European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis

Johnson¹,

Cordier²,

Lazor³

et al. 2009

European Respiratory Journal

466

561

View full text Add to dashboard Cite

“…1,3) In considering thoracic duct ligation, we performed thoracic duct scintigraphy to locate the injury site of the thoracic duct in the present case. However, our results showed diffuse accumulation of radiotracer in the left thoracic cavity and we did not identify its leakage site from the thoracic duct.…”

Section: Discussionmentioning

confidence: 99%

“…Surgical treatment options, such as pleuroperitoneal shunt and thoracic duct ligation, are also performed on patients with a large amount of pleural effusion. 1,3) We report the case of a mid-thirties female who developed severe chylothorax after bilateral lung transplantation for LAM and was treated successfully by injection of fibrin glue into the thoracic cavity.…”

Section: Introductionmentioning

confidence: 99%

A Case of Successful Therapy by Intrapleural Injection of Fibrin Glue for Chylothorax after Lung Transplantation for Lymphangioleiomyomatosis

Oishi

Hoshikawa

Sado

et al. 2017

ATCS

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A 37-year-old woman underwent bilateral lung transplantation for lymphangioleiomyomatosis. Dense pleural adhesions due to past pleurodesis for chylothorax were observed and dissected in both thoracic cavities. The patient developed chylothorax after transplant. Chylothorax in the right thoracic cavity was successfully treated by conventional pleurodesis; however, pleural effusion from the left thoracic cavity was not reduced. According to fluoroscopic images obtained by injecting a contrast medium through the chest tube, the remaining pleural space in the left thoracic cavity was small and localized in the lower region adjacent to the mediastinum. We opted to fill this space with fibrin glue; we injected fibrinogen and thrombin solution into the space through the chest tube. We performed fibrin glue treatment three times and pleural effusion was dramatically decreased. We removed the chest tube on day 107 post-transplant. No recurrent chylothorax has been recorded for 10 years after lung transplantation.

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