Lung Reduction Operation and Resection of Pulmonary Nodules in Patients With Severe Emphysema

Short and Long Term Results of Major Lung Resections in Very Elderly People

“…First papers addressing combined adequate cancer resection with volume reduction were published only in 1998 and were based on very small series of patients (5 and 14): all of them did well postoperatively and showed long term benefits in dyspnoea index, FEV1, and 6-minute walk test [24,25].…”

Lung Transplantation and Lung Volume Reduction Surgery versus Transplantation in Chronic Obstructive Pulmonary Disease

“…Patients with lung cancer are not candidates for lung transplantation; LVRS, however, has been performed successfully in patients with limited-stage non-small cell lung cancer along with cancer resection. These combined procedures have allowed for a potentially curative resection in patients who may have been limited by poor lung function in the traditional approach, and should be considered in selected individuals (21)(22)(23)(24)(25)(26)(27)(28). Other medical as well psychological and social factors may interfere with the patient's ability to maintain the consistent immunosuppressive regimen and medical follow-up that are crucial after transplantation, but may not be barriers for LVRS.…”

The Evaluation and Preparation of the Patient for Lung Volume Reduction Surgery

“…The presence of significant pleural or interstitial lung disease may also prevent LVRS. Although severe emphysema may preclude surgical resection of a pulmonary nodule, surgical techniques developed for LVRS have allowed resection of lung nodules previously believed to be unresectable because of respiratory limitations (5,6). Reactive airway disease is not a contraindication for LVRS; however, the presence of significant airway bronchoreactivity suggests that the primary disease process may be more of an inflammatory airway disease and thus less likely to improve after LVRS.…”