Lung procurement from a donor with a long-term left ventricular assist device

Ren, Dewei; Rodríguez, Limael E.; Blau, Lance; Bruckner, Brian A.; Loebe, Matthias

doi:10.1016/j.healun.2013.08.015

Cited by 6 publications

(5 citation statements)

References 3 publications

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“…Reports detailing the recovery of lungs with old-generation LVADs have been published. 1 , 2 , 3 One bilateral lung transplant was described in Europe 3 and none in the United States from a donor with HM 3. Lung recovery in the setting of previous LVAD implantation has its own challenges due to the risk of injury to the heart, lungs, outflow graft, and driveline.…”

Section: Discussionmentioning

confidence: 99%

Bilateral lung transplantation from a left ventricular assist device supported donor

Choi¹,

Spadaccio²,

Altarabsheh³

et al. 2023

JTCVS Techniques

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Section: Discussionmentioning

confidence: 99%

Bilateral lung transplantation from a left ventricular assist device supported donor

Choi¹,

Spadaccio²,

Altarabsheh³

et al. 2023

JTCVS Techniques

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“…To our knowledge, successful transplantation of lungs from a donor with mechanical circulatory support has been limited [3–5]. In these reports, donors were younger than our borderline age donor and the duration of LVAD support before retrieval varies from 1 day to 1 year after implantation.…”

Section: Discussionmentioning

confidence: 99%

“…For many years, brain dead patients with implanted mechanical circulatory support system have not been considered as potential lung donors. Recently, three cases of lung procurement from a donor with a circulatory support devices were reported [3–5]. …”

Section: Introductionmentioning

confidence: 99%

Ex-vivo recruitment and x-ray assessment of donor lungs in a challenging retrieval from a donor supported by lvad using the portable normothermic perfusion system: a case report

Schiavon

Calabrese

Gregorio

et al. 2017

J Cardiothorac Surg

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BackgroundLung transplantation (LTx) is limited by the shortage of suitable donors. To overcome this problem, many programs have begun to use donors with extended criteria (marginal donors). However, brain-dead patients with implanted mechanical circulatory support system have rarely been considered as potential lung donors. This case demonstrates the feasibility of lung transplantations from organ donors supported by a mechanical circulatory support system despite the possible difficulties of lung retrieval.Case presentationOur case presents a successful procurement and bilateral lung transplantation from a donor supported by a left ventricular assist device (LVAD) who experienced an intraoperatively haemodynamic complication. The use of portable normothermic perfusion device let us to reduce ischemic injury and assess these marginal donor lungs helping us to determine the clinical suitability for transplantation. Given our extensive experience with the device instrumentation and management, the EVLP process was uneventful with excellent post-transplant course.ConclusionsThis case report demonstrates the feasibility of lung transplantations from organ donors supported by a mechanical circulatory support system using the portable normothermic perfusion platform to assess and preserve these donor lungs.

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“…Currently, reviews on donor lung selection have not addressed cardiac assist devices, although previously we have described a case in which we used a lung from a donor who was supported by a LVAD. 4 In addition, in these high-risk donors, previous cardiopulmonary surgery has been perceived as a relative contraindication. 5,6 not all patients with mechanical circulatory support are suitable lung donors.…”

Section: Discussionmentioning

confidence: 99%

Lung Procurement from a Donor on ECMO Support

et al. 2015

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We report the case of a 50-year-old man with congestive heart failure who became a candidate for organ donation after anoxic brain injury after cardiopulmonary resuscitation (CPR) who was on a venoarterial extracorporeal membrane oxygenation (ECMO) support. On visualization, the donor's lung was acceptable for lung transplantation to a 68-year-old male patient with a chronic history of pulmonary fibrosis. Right single-lung implantation was successfully performed in the recipient. Herein, we report a case that highlights our institution's result suggesting that the use of a lung previously on ECMO support can safely and potentially expand the donor lung pool in carefully selected patients.

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Lung procurement from a donor with a long-term left ventricular assist device

Cited by 6 publications

References 3 publications

Bilateral lung transplantation from a left ventricular assist device supported donor

Bilateral lung transplantation from a left ventricular assist device supported donor

Ex-vivo recruitment and x-ray assessment of donor lungs in a challenging retrieval from a donor supported by lvad using the portable normothermic perfusion system: a case report

Lung Procurement from a Donor on ECMO Support

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