Lung metastases from cutaneous adenoid cystic carcinoma 23 years after initial treatment

Abstract

Cutaneous adenoid cystic carcinoma (CACC) is an extremely rare neoplasm of head and neck region, and is characterized by propensity for local recurrence and perineural invasion. Late distant metastases occur usually to lungs. Although patients with lung metastases from CACC cannot be cured, long-term survival may be possible due to its slow-growing malignancy. We report a case of a 69-year-old female with lung metastases from CACC 23 years after initial surgery of scalp nodule.

CT-guided palladium-103 seed brachytherapy for metastatic adenoid cystic carcinoma: a retrospective study to assess initial safety and effectiveness of percutaneous CT fluoroscopy-guided permanent seed brachytherapy

“…Adenoid cystic carcinoma is an uncommon secretory gland malignancy arising from a variety of head and neck sites, including major and minor salivary glands, palate, maxilla, and trachea [6,7]. While biologic behavior of the disease is poorly understood, it has been long recognized that ACC progresses slowly and has a high propensity for metastases and perineural invasion [10][11][12][13][14]. The most common site of metastases is the lungs, resulting in poor prognosis [11,12,15].…”